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Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study

(1) Background: It is not well known whether there is an association between COPD and hemorrhagic stroke (HS). We aim to analyze the incidence, clinical characteristics, procedures, and outcomes of HS in patients with and without COPD and to assess sex differences. Secondly, to identify factors asso...

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Autores principales: de Miguel-Diez, Javier, Lopez-Herranz, Marta, Jiménez-García, Rodrigo, Hernández-Barrera, Valentín, Jimenez-Trujillo, Isabel, de Miguel-Yanes, Jose M., Lopez de Andres, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200115/
https://www.ncbi.nlm.nih.gov/pubmed/34199919
http://dx.doi.org/10.3390/jcm10112491
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author de Miguel-Diez, Javier
Lopez-Herranz, Marta
Jiménez-García, Rodrigo
Hernández-Barrera, Valentín
Jimenez-Trujillo, Isabel
de Miguel-Yanes, Jose M.
Lopez de Andres, Ana
author_facet de Miguel-Diez, Javier
Lopez-Herranz, Marta
Jiménez-García, Rodrigo
Hernández-Barrera, Valentín
Jimenez-Trujillo, Isabel
de Miguel-Yanes, Jose M.
Lopez de Andres, Ana
author_sort de Miguel-Diez, Javier
collection PubMed
description (1) Background: It is not well known whether there is an association between COPD and hemorrhagic stroke (HS). We aim to analyze the incidence, clinical characteristics, procedures, and outcomes of HS in patients with and without COPD and to assess sex differences. Secondly, to identify factors associated with in-hospital mortality (IHM). (2) Methods: Patients aged ≥40 years hospitalized with HS included in the Spanish National Hospital Discharge Database (2016–2018) were analyzed. Propensity score matching (PSM) was used to compare patients according to sex and COPD status. (3) Results: We included 55,615 patients (44.29% women). Among men with COPD the HS adjusted incidence was higher (IRR 1.31; 95% CI 1.24–1.57) than among non-COPD men. COPD men had higher adjusted incidence of HS than COPD women (IRR 1.87; 95% CI 1.85–1.89). After matching, COPD men had a higher IHM (29.96% vs. 27.46%; p = 0.032) than non-COPD men. Decompressive craniectomy was more frequently conducted among COPD men than COPD women (6.74% vs. 4.54%; p = 0.014). IHM increased with age and atrial fibrillation, while decompressive craniectomy reduced IHM. (4) Conclusions: COPD men had higher incidence and IHM of HS than men without COPD. COPD men had higher incidence of HS than COPD women. Decompressive craniectomy was more frequently conducted in COPD men than COPD women and this procedure was associated to better survival.
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spelling pubmed-82001152021-06-14 Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study de Miguel-Diez, Javier Lopez-Herranz, Marta Jiménez-García, Rodrigo Hernández-Barrera, Valentín Jimenez-Trujillo, Isabel de Miguel-Yanes, Jose M. Lopez de Andres, Ana J Clin Med Article (1) Background: It is not well known whether there is an association between COPD and hemorrhagic stroke (HS). We aim to analyze the incidence, clinical characteristics, procedures, and outcomes of HS in patients with and without COPD and to assess sex differences. Secondly, to identify factors associated with in-hospital mortality (IHM). (2) Methods: Patients aged ≥40 years hospitalized with HS included in the Spanish National Hospital Discharge Database (2016–2018) were analyzed. Propensity score matching (PSM) was used to compare patients according to sex and COPD status. (3) Results: We included 55,615 patients (44.29% women). Among men with COPD the HS adjusted incidence was higher (IRR 1.31; 95% CI 1.24–1.57) than among non-COPD men. COPD men had higher adjusted incidence of HS than COPD women (IRR 1.87; 95% CI 1.85–1.89). After matching, COPD men had a higher IHM (29.96% vs. 27.46%; p = 0.032) than non-COPD men. Decompressive craniectomy was more frequently conducted among COPD men than COPD women (6.74% vs. 4.54%; p = 0.014). IHM increased with age and atrial fibrillation, while decompressive craniectomy reduced IHM. (4) Conclusions: COPD men had higher incidence and IHM of HS than men without COPD. COPD men had higher incidence of HS than COPD women. Decompressive craniectomy was more frequently conducted in COPD men than COPD women and this procedure was associated to better survival. MDPI 2021-06-04 /pmc/articles/PMC8200115/ /pubmed/34199919 http://dx.doi.org/10.3390/jcm10112491 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Miguel-Diez, Javier
Lopez-Herranz, Marta
Jiménez-García, Rodrigo
Hernández-Barrera, Valentín
Jimenez-Trujillo, Isabel
de Miguel-Yanes, Jose M.
Lopez de Andres, Ana
Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title_full Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title_fullStr Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title_full_unstemmed Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title_short Effect of COPD on the Hospital Outcomes and Mortality among Hemorrhagic Stroke Patients. Sex Differences in a Population-Based Study
title_sort effect of copd on the hospital outcomes and mortality among hemorrhagic stroke patients. sex differences in a population-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200115/
https://www.ncbi.nlm.nih.gov/pubmed/34199919
http://dx.doi.org/10.3390/jcm10112491
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