Cargando…

Novel Strategies for Disrupting Cancer-Cell Functions with Mitochondria-Targeted Antitumor Drug–Loaded Nanoformulations

Any variation in normal cellular function results in mitochondrial dysregulation that occurs in several diseases, including cancer. Such processes as oxidative stress, metabolism, signaling, and biogenesis play significant roles in cancer initiation and progression. Due to their central role in cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	S Allemailem, Khaled, Almatroudi, Ahmad, Alsahli, Mohammed A, Aljaghwani, Aseel, M El-Kady, Asmaa, Rahmani, Arshad Husain, Khan, Amjad Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200140/ https://www.ncbi.nlm.nih.gov/pubmed/34135584 http://dx.doi.org/10.2147/IJN.S303832

Ejemplares similares

Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
por: Allemailem, Khaled S, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress Provocation by Different Nanoparticles: An Innovative Approach to Manage the Cancer and Other Common Diseases
por: Khan, Amjad Ali, et al.
Publicado: (2020)

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
por: Allemailem, Khaled S., et al.
Publicado: (2022)

Potential Therapeutic Targets of Quercetin, a Plant Flavonol, and Its Role in the Therapy of Various Types of Cancer through the Modulation of Various Cell Signaling Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2021)

Antimicrobial, Immunomodulatory and Anti-Inflammatory Potential of Liposomal Thymoquinone: Implications in the Treatment of Bacterial Pneumonia in Immunocompromised Mice
por: Allemailem, Khaled S., et al.
Publicado: (2021)

Safety and Therapeutic Efficacy of Thymoquinone-Loaded Liposomes against Drug-Sensitive and Drug-Resistant Acinetobacter baumannii
por: Allemailem, Khaled S., et al.
Publicado: (2021)

The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

Manifestations of renal system involvement in hospitalized patients with COVID-19 in Saudi Arabia
por: Allemailem, Khaled S., et al.
Publicado: (2021)

The Multifaceted Role of Baicalein in Cancer Management through Modulation of Cell Signalling Pathways
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

Role of Ajwa Date Fruit Pulp and Seed in the Management of Diseases through In Vitro and In Silico Analysis
por: Anwar, Shehwaz, et al.
Publicado: (2022)

Thymoquinone, an Active Constituent of Black Seed Attenuates CCl4 Induced Liver Injury in Mice via Modulation of Antioxidant Enzymes, PTEN, P53 and VEGF Protein
por: Rahmani, Arshad Husain, et al.
Publicado: (2019)

Regulation of Pro-Inflammatory Macrophage Polarization via Lipid Nanoparticles Mediated Delivery of Anti-Prostaglandin-E2 siRNA
por: Almatroudi, Ahmad, et al.
Publicado: (2022)

Innovative Strategies of Reprogramming Immune System Cells by Targeting CRISPR/Cas9-Based Genome-Editing Tools: A New Era of Cancer Management
por: Allemailem, Khaled S, et al.
Publicado: (2023)

Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Psychiatric Disorders of Neurocysticercosis: Narrative Review
por: El-Kady, Asmaa M, et al.
Publicado: (2021)

Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
por: Almatroudi, Ahmad, et al.
Publicado: (2023)

The Potential Role of Apigenin in Cancer Prevention and Treatment
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity
por: Alsahli, Mohammed A., et al.
Publicado: (2021)

Therapeutic Effect of Bilsaan, Sambucus nigra Stem Exudate, on the OVA-Induced Allergic Asthma in Mice
por: Alrumaihi, Faris, et al.
Publicado: (2020)

Genetic Diversity of Schistosoma haematobium in Qena Governorate, Upper Egypt
por: El-Kady, Asmaa M, et al.
Publicado: (2020)

Potential Therapeutic Targets of Formononetin, a Type of Methoxylated Isoflavone, and Its Role in Cancer Therapy through the Modulation of Signal Transduction Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2023)

Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
por: Allemailem, Khaled S., et al.
Publicado: (2023)

Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

A Compendium of Perspectives on Diabetes: A Challenge for Sustainable Health in the Modern Era
por: Verma, Amit K, et al.
Publicado: (2021)

Potential Antitumor Effects of Pomegranates and Its Ingredients
por: Rahmani, Arshad H., et al.
Publicado: (2017)

Potential of Methylglyoxal-Conjugated Chitosan Nanoparticles in Treatment of Fluconazole-Resistant Candida albicans Infection in a Murine Model
por: Khan, Shaheer Hasan, et al.
Publicado: (2020)

Methanolic Fenugreek Seed Extract Induces p53-Dependent Mitotic Catastrophe in Breast Cancer Cells, Leading to Apoptosis
por: Alrumaihi, Faris A, et al.
Publicado: (2021)

Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress and Inflammation
por: Alzohairy, Mohammad A., et al.
Publicado: (2021)

SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy
por: Rafat, Sahar, et al.
Publicado: (2022)

Myeloperoxidase as an Active Disease Biomarker: Recent Biochemical and Pathological Perspectives
por: Khan, Amjad A., et al.
Publicado: (2018)

Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice
por: Khan, Arif, et al.
Publicado: (2020)

Role of Cytokines and Chemokines in NSCLC Immune Navigation and Proliferation
por: Ramachandran, Sowmya, et al.
Publicado: (2021)

Effect of Exposure to Cement Dust among the Workers: An Evaluation of Health Related Complications
por: Rahmani, Arshad H., et al.
Publicado: (2018)

Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2022)

Prevalence and Significance of Pyuria in Chronic Kidney Disease Patients in Saudi Arabia
por: Almaiman, Lina, et al.
Publicado: (2021)

Encapsulation of MERS antigen into α-GalCer-bearing-liposomes elicits stronger effector and memory immune responses in immunocompetent and leukopenic mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Association of Genetic Variants of KCNJ11 and KCNQ1 Genes with Risk of Type 2 Diabetes Mellitus (T2DM) in the Indian Population: A Case-Control Study
por: Khan, Vasiuddin, et al.
Publicado: (2020)

Potential Therapeutic Targets of Resveratrol, a Plant Polyphenol, and Its Role in the Therapy of Various Types of Cancer
por: Almatroodi, Saleh A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t95pefe962cufp5ctqnbr5ttev