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An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy

The increase in antibacterial resistance is a serious challenge for both the health and defence sectors and there is a need for both novel antibacterial targets and antibacterial strategies. RNA degradation and ribonucleases, such as the essential endoribonuclease RNase E, encoded by the rne gene, a...

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Detalles Bibliográficos
Autores principales:	Goddard, Layla R., Mardle, Charlotte E., Gneid, Hassan, Ball, Ciara G., Gowers, Darren M., Atkins, Helen S., Butt, Louise E., Watts, Jonathan K., Vincent, Helen A., Callaghan, Anastasia J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200214/ https://www.ncbi.nlm.nih.gov/pubmed/34200016 http://dx.doi.org/10.3390/molecules26113414

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