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PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-

Observing the positive effects of PRP (platelet-rich plasma) used in various pathologies, both in traumatology, orthopedics, sports medicine, and in plastic and reconstructive surgery, we decided to develop an improved product, using granular hyaluronic acid. The paper aims at establishing a protoco...

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Autores principales: MARINESCU, ELENA-ALEXANDRA, NICA, OLIVIU, ILINOIU, ENIO, COJOCARU, ANCA, NEGRILĂ, ALINA ALEXANDRA, CIUREA, MARIUS EUGEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200601/
https://www.ncbi.nlm.nih.gov/pubmed/34211746
http://dx.doi.org/10.12865/CHSJ.47.01.07
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author MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
COJOCARU, ANCA
NEGRILĂ, ALINA ALEXANDRA
CIUREA, MARIUS EUGEN
author_facet MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
COJOCARU, ANCA
NEGRILĂ, ALINA ALEXANDRA
CIUREA, MARIUS EUGEN
author_sort MARINESCU, ELENA-ALEXANDRA
collection PubMed
description Observing the positive effects of PRP (platelet-rich plasma) used in various pathologies, both in traumatology, orthopedics, sports medicine, and in plastic and reconstructive surgery, we decided to develop an improved product, using granular hyaluronic acid. The paper aims at establishing a protocol for obtaining PRP enriched with hyaluronic acid, which can be used in the current practice of treatment of skin defects, safely, with minimal side effects and limited possible, but to provide a shorter healing period as compared to native, "free" healing. The experiment aims to find an effective and rapid method of healing wounds with skin defects, by using a local adjuvant (PRP enriched with hyaluronic acid), which is available to any plastic surgeon. Following the combination of PRP with granular hyaluronic acid, we obtained a product that macroscopically has a gelatinous, viscous consistency, with a good adhesion to the tissues. The potential benefits of this experiment could be the basis for the development of treatment protocols for various pathologies, which result in wounds with skin defects, the most important aspect being the shortening of the classic healing period.
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spelling pubmed-82006012021-06-30 PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation- MARINESCU, ELENA-ALEXANDRA NICA, OLIVIU ILINOIU, ENIO COJOCARU, ANCA NEGRILĂ, ALINA ALEXANDRA CIUREA, MARIUS EUGEN Curr Health Sci J Original Paper Observing the positive effects of PRP (platelet-rich plasma) used in various pathologies, both in traumatology, orthopedics, sports medicine, and in plastic and reconstructive surgery, we decided to develop an improved product, using granular hyaluronic acid. The paper aims at establishing a protocol for obtaining PRP enriched with hyaluronic acid, which can be used in the current practice of treatment of skin defects, safely, with minimal side effects and limited possible, but to provide a shorter healing period as compared to native, "free" healing. The experiment aims to find an effective and rapid method of healing wounds with skin defects, by using a local adjuvant (PRP enriched with hyaluronic acid), which is available to any plastic surgeon. Following the combination of PRP with granular hyaluronic acid, we obtained a product that macroscopically has a gelatinous, viscous consistency, with a good adhesion to the tissues. The potential benefits of this experiment could be the basis for the development of treatment protocols for various pathologies, which result in wounds with skin defects, the most important aspect being the shortening of the classic healing period. Medical University Publishing House Craiova 2021 2021-03-31 /pmc/articles/PMC8200601/ /pubmed/34211746 http://dx.doi.org/10.12865/CHSJ.47.01.07 Text en Copyright © 2014, Medical University Publishing House Craiova https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
COJOCARU, ANCA
NEGRILĂ, ALINA ALEXANDRA
CIUREA, MARIUS EUGEN
PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title_full PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title_fullStr PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title_full_unstemmed PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title_short PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation-
title_sort prp enriched with hyaluronic acid -prp from rat protocol and method of preparation-
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200601/
https://www.ncbi.nlm.nih.gov/pubmed/34211746
http://dx.doi.org/10.12865/CHSJ.47.01.07
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