Cargando…

Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature

Crohn's disease represents an inflammatory bowel disease of unknown etiology, with chronic evolution, which may affect any segment of the digestive tract. The main classes of drugs used in patients with inflammatory bowel disease include: aminosalicylates, corticosteroids, immunosuppressants, b...

Descripción completa

Detalles Bibliográficos
Autores principales: STATIE, RĂZVAN-CRISTIAN, FLORESCU, DAN NICOLAE, GHEONEA, DAN-IONUŢ, CIUREA, TUDOREL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200608/
https://www.ncbi.nlm.nih.gov/pubmed/34211761
http://dx.doi.org/10.12865/CHSJ.47.01.22
_version_ 1783707643757461504
author STATIE, RĂZVAN-CRISTIAN
FLORESCU, DAN NICOLAE
GHEONEA, DAN-IONUŢ
CIUREA, TUDOREL
author_facet STATIE, RĂZVAN-CRISTIAN
FLORESCU, DAN NICOLAE
GHEONEA, DAN-IONUŢ
CIUREA, TUDOREL
author_sort STATIE, RĂZVAN-CRISTIAN
collection PubMed
description Crohn's disease represents an inflammatory bowel disease of unknown etiology, with chronic evolution, which may affect any segment of the digestive tract. The main classes of drugs used in patients with inflammatory bowel disease include: aminosalicylates, corticosteroids, immunosuppressants, biological agents and antibiotics. Biological therapy with anti-TNF-α agents offers significant therapeutic benefits, but their use requires caution, as they can also be associated with numerous side effects. We present the case of a female patient known with Crohn's disease, under going biological therapy with adalimumab, who developed a complication, quite rarely described in the literature, possibly as a result of treatment with anti-TNF-α agents.
format Online
Article
Text
id pubmed-8200608
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Medical University Publishing House Craiova
record_format MEDLINE/PubMed
spelling pubmed-82006082021-06-30 Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature STATIE, RĂZVAN-CRISTIAN FLORESCU, DAN NICOLAE GHEONEA, DAN-IONUŢ CIUREA, TUDOREL Curr Health Sci J Case Report Crohn's disease represents an inflammatory bowel disease of unknown etiology, with chronic evolution, which may affect any segment of the digestive tract. The main classes of drugs used in patients with inflammatory bowel disease include: aminosalicylates, corticosteroids, immunosuppressants, biological agents and antibiotics. Biological therapy with anti-TNF-α agents offers significant therapeutic benefits, but their use requires caution, as they can also be associated with numerous side effects. We present the case of a female patient known with Crohn's disease, under going biological therapy with adalimumab, who developed a complication, quite rarely described in the literature, possibly as a result of treatment with anti-TNF-α agents. Medical University Publishing House Craiova 2021 2021-03-31 /pmc/articles/PMC8200608/ /pubmed/34211761 http://dx.doi.org/10.12865/CHSJ.47.01.22 Text en Copyright © 2014, Medical University Publishing House Craiova https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Report
STATIE, RĂZVAN-CRISTIAN
FLORESCU, DAN NICOLAE
GHEONEA, DAN-IONUŢ
CIUREA, TUDOREL
Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title_full Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title_fullStr Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title_full_unstemmed Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title_short Rare Complication During Anti-TNF-α Treatment in a Patient with Crohn’s Disease: A Case Report and Review of the Literature
title_sort rare complication during anti-tnf-α treatment in a patient with crohn’s disease: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200608/
https://www.ncbi.nlm.nih.gov/pubmed/34211761
http://dx.doi.org/10.12865/CHSJ.47.01.22
work_keys_str_mv AT statierazvancristian rarecomplicationduringantitnfatreatmentinapatientwithcrohnsdiseaseacasereportandreviewoftheliterature
AT florescudannicolae rarecomplicationduringantitnfatreatmentinapatientwithcrohnsdiseaseacasereportandreviewoftheliterature
AT gheoneadanionut rarecomplicationduringantitnfatreatmentinapatientwithcrohnsdiseaseacasereportandreviewoftheliterature
AT ciureatudorel rarecomplicationduringantitnfatreatmentinapatientwithcrohnsdiseaseacasereportandreviewoftheliterature