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Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults
According to GLOBOCAN 2018 data Colorectal cancer (CRC) represents the third most commonly diagnosed cancer in the world and has the second-highest mortality rate. The incidence of CRC has been rising worldwide, the majority of cases being in developing countries mostly due to the adoption of an unh...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medical University Publishing House Craiova
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200615/ https://www.ncbi.nlm.nih.gov/pubmed/34211752 http://dx.doi.org/10.12865/CHSJ.47.01.13 |
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author | PETRE-MANDACHE, CARMEN-BIANCA MARGARITESCU, DRAGOS NICOLAE MITRUT, RADU KAMAL, ADINA-MARIA PADUREANU, VLAD CUCU, MIHAI-GABRIEL MITRUT, PAUL |
author_facet | PETRE-MANDACHE, CARMEN-BIANCA MARGARITESCU, DRAGOS NICOLAE MITRUT, RADU KAMAL, ADINA-MARIA PADUREANU, VLAD CUCU, MIHAI-GABRIEL MITRUT, PAUL |
author_sort | PETRE-MANDACHE, CARMEN-BIANCA |
collection | PubMed |
description | According to GLOBOCAN 2018 data Colorectal cancer (CRC) represents the third most commonly diagnosed cancer in the world and has the second-highest mortality rate. The incidence of CRC has been rising worldwide, the majority of cases being in developing countries mostly due to the adoption of an unhealthy lifestyle. The main driving factors behind CRC are a sedentary lifestyle, obesity, red meat consumption, alcohol, and tobacco; however, early detection screenings and standardized treatment options have reduced CRC mortality. Better family history and genetic testing can help those with a hereditary predisposition in taking preventative measures. |
format | Online Article Text |
id | pubmed-8200615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Medical University Publishing House Craiova |
record_format | MEDLINE/PubMed |
spelling | pubmed-82006152021-06-30 Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults PETRE-MANDACHE, CARMEN-BIANCA MARGARITESCU, DRAGOS NICOLAE MITRUT, RADU KAMAL, ADINA-MARIA PADUREANU, VLAD CUCU, MIHAI-GABRIEL MITRUT, PAUL Curr Health Sci J Original Paper According to GLOBOCAN 2018 data Colorectal cancer (CRC) represents the third most commonly diagnosed cancer in the world and has the second-highest mortality rate. The incidence of CRC has been rising worldwide, the majority of cases being in developing countries mostly due to the adoption of an unhealthy lifestyle. The main driving factors behind CRC are a sedentary lifestyle, obesity, red meat consumption, alcohol, and tobacco; however, early detection screenings and standardized treatment options have reduced CRC mortality. Better family history and genetic testing can help those with a hereditary predisposition in taking preventative measures. Medical University Publishing House Craiova 2021 2021-03-31 /pmc/articles/PMC8200615/ /pubmed/34211752 http://dx.doi.org/10.12865/CHSJ.47.01.13 Text en Copyright © 2014, Medical University Publishing House Craiova https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited. |
spellingShingle | Original Paper PETRE-MANDACHE, CARMEN-BIANCA MARGARITESCU, DRAGOS NICOLAE MITRUT, RADU KAMAL, ADINA-MARIA PADUREANU, VLAD CUCU, MIHAI-GABRIEL MITRUT, PAUL Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title | Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title_full | Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title_fullStr | Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title_full_unstemmed | Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title_short | Risk Factors and Genetic Predisposition in Colorectal Cancer: A Study on Young and Old Adults |
title_sort | risk factors and genetic predisposition in colorectal cancer: a study on young and old adults |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200615/ https://www.ncbi.nlm.nih.gov/pubmed/34211752 http://dx.doi.org/10.12865/CHSJ.47.01.13 |
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