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Basal Cell Carcinoma and its Impact on Different Anatomical Regions

Basal cell carcinoma (BCC) is the most common skin cancer. We conducted a retrospective study over a period of two years (2018-2019), on 214 patients from the Plastic Surgery clinic in order to identify the clinical and histopathological aspects of the disease: the case distribution according to sex...

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Autores principales: COJOCARU, ANCA, MARINESCU, ELENA-ALEXANDRA, NICA, OLIVIU, ILINOIU, ENIO, NEGRILA, ALINA, CIUREA, MARIUS-EUGEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200622/
https://www.ncbi.nlm.nih.gov/pubmed/34211751
http://dx.doi.org/10.12865/CHSJ.47.01.12
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author COJOCARU, ANCA
MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
NEGRILA, ALINA
CIUREA, MARIUS-EUGEN
author_facet COJOCARU, ANCA
MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
NEGRILA, ALINA
CIUREA, MARIUS-EUGEN
author_sort COJOCARU, ANCA
collection PubMed
description Basal cell carcinoma (BCC) is the most common skin cancer. We conducted a retrospective study over a period of two years (2018-2019), on 214 patients from the Plastic Surgery clinic in order to identify the clinical and histopathological aspects of the disease: the case distribution according to sex, living environment, age, histopathological subtype, location. Results. The F/M ratio was of 1.03 in favour of women. The incidence was higher for patients from rural areas (55.14%). The most affected group age was between 70-80 years old, with 76 patients (35.51%). The most frequent histological type was nodular basal cell carcinoma (65.42%), followed by micronodular subtype (17.29%). We observed the association of basal cell carcinoma with a number of other conditions such as: high blood pressure (92 cases), diabetes (19 cases), chronic kidney disease (2 cases), liver disease (5 cases), epilepsy (2 cases). Correlating the histopathological subtype and the invasion of the edges of the surgical excision specimen, we noticed that edge invasion was present: in the case of nodular basal cell carcinoma (15.71%), micronodular subtype (43.24%), superficial subtype (50%), morpheaform subtype (40%). Dividing the cases by location, we highlighted the risk areas: nasal region (29.44%), cheek (10.75%), orbital region (13.55%), scalp (10.75%), auricular region (7.48%), forehead (8.41%), etc. Thus, 89.72% of cases were located on photo-exposed areas (head and neck). Patients from rural areas registered a higher number of cases both in photo-exposed and non-exposed areas.
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spelling pubmed-82006222021-06-30 Basal Cell Carcinoma and its Impact on Different Anatomical Regions COJOCARU, ANCA MARINESCU, ELENA-ALEXANDRA NICA, OLIVIU ILINOIU, ENIO NEGRILA, ALINA CIUREA, MARIUS-EUGEN Curr Health Sci J Original Paper Basal cell carcinoma (BCC) is the most common skin cancer. We conducted a retrospective study over a period of two years (2018-2019), on 214 patients from the Plastic Surgery clinic in order to identify the clinical and histopathological aspects of the disease: the case distribution according to sex, living environment, age, histopathological subtype, location. Results. The F/M ratio was of 1.03 in favour of women. The incidence was higher for patients from rural areas (55.14%). The most affected group age was between 70-80 years old, with 76 patients (35.51%). The most frequent histological type was nodular basal cell carcinoma (65.42%), followed by micronodular subtype (17.29%). We observed the association of basal cell carcinoma with a number of other conditions such as: high blood pressure (92 cases), diabetes (19 cases), chronic kidney disease (2 cases), liver disease (5 cases), epilepsy (2 cases). Correlating the histopathological subtype and the invasion of the edges of the surgical excision specimen, we noticed that edge invasion was present: in the case of nodular basal cell carcinoma (15.71%), micronodular subtype (43.24%), superficial subtype (50%), morpheaform subtype (40%). Dividing the cases by location, we highlighted the risk areas: nasal region (29.44%), cheek (10.75%), orbital region (13.55%), scalp (10.75%), auricular region (7.48%), forehead (8.41%), etc. Thus, 89.72% of cases were located on photo-exposed areas (head and neck). Patients from rural areas registered a higher number of cases both in photo-exposed and non-exposed areas. Medical University Publishing House Craiova 2021 2021-03-31 /pmc/articles/PMC8200622/ /pubmed/34211751 http://dx.doi.org/10.12865/CHSJ.47.01.12 Text en Copyright © 2014, Medical University Publishing House Craiova https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
COJOCARU, ANCA
MARINESCU, ELENA-ALEXANDRA
NICA, OLIVIU
ILINOIU, ENIO
NEGRILA, ALINA
CIUREA, MARIUS-EUGEN
Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title_full Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title_fullStr Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title_full_unstemmed Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title_short Basal Cell Carcinoma and its Impact on Different Anatomical Regions
title_sort basal cell carcinoma and its impact on different anatomical regions
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200622/
https://www.ncbi.nlm.nih.gov/pubmed/34211751
http://dx.doi.org/10.12865/CHSJ.47.01.12
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