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m7G Methyltransferase METTL1 Promotes Post-ischemic Angiogenesis via Promoting VEGFA mRNA Translation

Post-transcriptional modifications play pivotal roles in various pathological processes and ischemic disorders. However, the role of N7-methylguanosine (m7G), particularly m7G in mRNA, on post-ischemic angiogenesis remains largely unknown. Here, we identified that methyltransferase like 1 (METTL1) w...

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Detalles Bibliográficos
Autores principales: Zhao, Yongchao, Kong, Lingqiu, Pei, Zhiqiang, Li, Fuhai, Li, Chaofu, Sun, Xiaolei, Shi, Bei, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200671/
https://www.ncbi.nlm.nih.gov/pubmed/34136476
http://dx.doi.org/10.3389/fcell.2021.642080