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Aerobic Exercise Restores Aging‐Associated Reductions in Arterial Adropin Levels and Improves Adropin‐Induced Nitric Oxide‐Dependent Vasorelaxation
BACKGROUND: Adropin is a peptide hormone that promotes nitric oxide (NO) production via activation of endothelial NO synthase (eNOS) in endothelial cells. Its circulating levels are reduced with aging and increased with aerobic exercise training (AT). Using a mouse model, we hypothesized that AT res...
Autores principales: | Fujie, Shumpei, Hasegawa, Natsuki, Horii, Naoki, Uchida, Masataka, Sanada, Kiyoshi, Hamaoka, Takafumi, Padilla, Jaume, Martinez‐Lemus, Luis A., Maeda, Seiji, Iemitsu, Motoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200711/ https://www.ncbi.nlm.nih.gov/pubmed/33938228 http://dx.doi.org/10.1161/JAHA.120.020641 |
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