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Protective Functions of Liver X Receptor α in Established Vulnerable Plaques: Involvement of Regulating Endoplasmic Reticulum–Mediated Macrophage Apoptosis and Efferocytosis

BACKGROUND: Liver X receptor (LXR) belongs to the metabolic nuclear receptor superfamily, which plays a critical regulatory role in vascular physiology/pathology. However, effects of systemic LXR activation on established vulnerable plaques and the potential isotype‐specific role involved remain unc...

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Detalles Bibliográficos
Autores principales: Che, Xinyu, Xiao, Qingqing, Song, Wei, Zhang, Hengyuan, Sun, Beibei, Geng, Na, Tao, Zhenyu, Shao, Qin, Pu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200716/
https://www.ncbi.nlm.nih.gov/pubmed/33969692
http://dx.doi.org/10.1161/JAHA.120.018455