Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease

BACKGROUND: Myxomatous mitral valve disease (MMVD), a naturally occurring heart disease, affects 10% to 15% of the canine population. Canine MMVD shares many similarities with human MMVD. Untargeted metabolomics was performed to identify changes in metabolic pathways and biomarkers with potential cl...

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Detalles Bibliográficos
Autores principales: Li, Qinghong, Larouche‐Lebel, Éva, Loughran, Kerry A., Huh, Terry P., Suchodolski, Jan S., Oyama, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200728/
https://www.ncbi.nlm.nih.gov/pubmed/33890477
http://dx.doi.org/10.1161/JAHA.120.018923

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