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Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study

BACKGROUND: Dialysis‐requiring acute kidney injury (D‐AKI) is a major complication of cardiovascular surgery that results in worse prognosis. However, the incidence and impacts of D‐AKI in different types of cardiac surgeries have not been fully investigated. METHODS AND RESULTS: Patients admitted f...

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Autores principales: Chen, Jia‐Jin, Chang, Chih‐Hsiang, Wu, Victor Chien‐Chia, Chang, Shang‐Hung, Hung, Kuo‐Chun, Chu, Pao‐Hsien, Chen, Shao‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200754/
https://www.ncbi.nlm.nih.gov/pubmed/33880935
http://dx.doi.org/10.1161/JAHA.120.019718
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author Chen, Jia‐Jin
Chang, Chih‐Hsiang
Wu, Victor Chien‐Chia
Chang, Shang‐Hung
Hung, Kuo‐Chun
Chu, Pao‐Hsien
Chen, Shao‐Wei
author_facet Chen, Jia‐Jin
Chang, Chih‐Hsiang
Wu, Victor Chien‐Chia
Chang, Shang‐Hung
Hung, Kuo‐Chun
Chu, Pao‐Hsien
Chen, Shao‐Wei
author_sort Chen, Jia‐Jin
collection PubMed
description BACKGROUND: Dialysis‐requiring acute kidney injury (D‐AKI) is a major complication of cardiovascular surgery that results in worse prognosis. However, the incidence and impacts of D‐AKI in different types of cardiac surgeries have not been fully investigated. METHODS AND RESULTS: Patients admitted for cardiovascular surgery between July 1, 2004, and December 31, 2013, were identified from the National Health Insurance Research Database of Taiwan. The patients were grouped into D‐AKI (n=3089) and non–D‐AKI (n=42 151) groups. The outcome was all‐cause mortality and major adverse kidney event. The long‐term outcomes were worse in the D‐AKI group than the non–D‐AKI group (hazard ratio [HR], 3.89; 95% CI, 3.79–3.99 for major adverse kidney event; HR, 2.89; 95% CI, 2.81–2.98 for all‐cause mortality). Patients who underwent aortic surgery had higher risk for D‐AKI than other types of surgeries, but they were also more likely to recover. The long‐term dialysis rate for the patients who recovered from D‐AKI was also lowest in those who underwent aortic surgery. Among all types of cardiac surgeries with D‐AKI, patients who had heart valve surgery exhibited the greatest risks of all‐cause mortality (HR, 6.04; 95% CI, 5.78–6.32). CONCLUSIONS: Compared with other heart surgeries, aortic surgery resulted in a higher incidence of D‐AKI but better renal recovery, better short‐term outcome, and lower incidences of long‐term dialysis.
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spelling pubmed-82007542021-06-15 Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study Chen, Jia‐Jin Chang, Chih‐Hsiang Wu, Victor Chien‐Chia Chang, Shang‐Hung Hung, Kuo‐Chun Chu, Pao‐Hsien Chen, Shao‐Wei J Am Heart Assoc Original Research BACKGROUND: Dialysis‐requiring acute kidney injury (D‐AKI) is a major complication of cardiovascular surgery that results in worse prognosis. However, the incidence and impacts of D‐AKI in different types of cardiac surgeries have not been fully investigated. METHODS AND RESULTS: Patients admitted for cardiovascular surgery between July 1, 2004, and December 31, 2013, were identified from the National Health Insurance Research Database of Taiwan. The patients were grouped into D‐AKI (n=3089) and non–D‐AKI (n=42 151) groups. The outcome was all‐cause mortality and major adverse kidney event. The long‐term outcomes were worse in the D‐AKI group than the non–D‐AKI group (hazard ratio [HR], 3.89; 95% CI, 3.79–3.99 for major adverse kidney event; HR, 2.89; 95% CI, 2.81–2.98 for all‐cause mortality). Patients who underwent aortic surgery had higher risk for D‐AKI than other types of surgeries, but they were also more likely to recover. The long‐term dialysis rate for the patients who recovered from D‐AKI was also lowest in those who underwent aortic surgery. Among all types of cardiac surgeries with D‐AKI, patients who had heart valve surgery exhibited the greatest risks of all‐cause mortality (HR, 6.04; 95% CI, 5.78–6.32). CONCLUSIONS: Compared with other heart surgeries, aortic surgery resulted in a higher incidence of D‐AKI but better renal recovery, better short‐term outcome, and lower incidences of long‐term dialysis. John Wiley and Sons Inc. 2021-04-21 /pmc/articles/PMC8200754/ /pubmed/33880935 http://dx.doi.org/10.1161/JAHA.120.019718 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Chen, Jia‐Jin
Chang, Chih‐Hsiang
Wu, Victor Chien‐Chia
Chang, Shang‐Hung
Hung, Kuo‐Chun
Chu, Pao‐Hsien
Chen, Shao‐Wei
Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title_full Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title_fullStr Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title_full_unstemmed Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title_short Long‐Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population‐Based Study
title_sort long‐term outcomes of acute kidney injury after different types of cardiac surgeries: a population‐based study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200754/
https://www.ncbi.nlm.nih.gov/pubmed/33880935
http://dx.doi.org/10.1161/JAHA.120.019718
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