Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

BACKGROUND: Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of...

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Detalles Bibliográficos
Autores principales: D’Erasmo, Laura, Minicocci, Ilenia, Di Costanzo, Alessia, Pigna, Giovanni, Commodari, Daniela, Ceci, Fabrizio, Montali, Anna, Brancato, Francesca, Stanca, Ilaria, Nicolucci, Antonio, Ascione, Andrea, Galea, Nicola, Carbone, Iacopo, Francone, Marco, Maranghi, Marianna, Arca, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200757/
https://www.ncbi.nlm.nih.gov/pubmed/33890476
http://dx.doi.org/10.1161/JAHA.120.018932

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