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Cooperative binding ensures the obligatory melibiose/Na(+) cotransport in MelB

MelB catalyzes the obligatory cotransport of melibiose with Na(+), Li(+), or H(+). Crystal structure determination of the Salmonella typhimurium MelB (MelB(St)) has revealed a typical major facilitator superfamily (MFS) fold at a periplasmic open conformation. Cooperative binding of Na(+) and melibi...

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Detalles Bibliográficos
Autores principales: Hariharan, Parameswaran, Guan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200842/
https://www.ncbi.nlm.nih.gov/pubmed/34110360
http://dx.doi.org/10.1085/jgp.202012710

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