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Cooperative binding ensures the obligatory melibiose/Na(+) cotransport in MelB
MelB catalyzes the obligatory cotransport of melibiose with Na(+), Li(+), or H(+). Crystal structure determination of the Salmonella typhimurium MelB (MelB(St)) has revealed a typical major facilitator superfamily (MFS) fold at a periplasmic open conformation. Cooperative binding of Na(+) and melibi...
Autores principales: | Hariharan, Parameswaran, Guan, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200842/ https://www.ncbi.nlm.nih.gov/pubmed/34110360 http://dx.doi.org/10.1085/jgp.202012710 |
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