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Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction

SIMPLE SUMMARY: Transoral robotic surgery (TORS) with spontaneous healing is associated with improved quality of life as compared to traditional open surgery in small pharyngeal tumors. Improved surgeon experience allows very large or very complex resections, such as in a previously irradiated field...

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Autores principales: Gorphe, Philippe, Temam, Stéphane, Moya-Plana, Antoine, Leymarie, Nicolas, Kolb, Frédéric, Bout-Roumazeilles, Apolline, Qassemyar, Quentin, Benmoussa, Nadia, Honart, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201082/
https://www.ncbi.nlm.nih.gov/pubmed/34204149
http://dx.doi.org/10.3390/cancers13112831
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author Gorphe, Philippe
Temam, Stéphane
Moya-Plana, Antoine
Leymarie, Nicolas
Kolb, Frédéric
Bout-Roumazeilles, Apolline
Qassemyar, Quentin
Benmoussa, Nadia
Honart, Jean-François
author_facet Gorphe, Philippe
Temam, Stéphane
Moya-Plana, Antoine
Leymarie, Nicolas
Kolb, Frédéric
Bout-Roumazeilles, Apolline
Qassemyar, Quentin
Benmoussa, Nadia
Honart, Jean-François
author_sort Gorphe, Philippe
collection PubMed
description SIMPLE SUMMARY: Transoral robotic surgery (TORS) with spontaneous healing is associated with improved quality of life as compared to traditional open surgery in small pharyngeal tumors. Improved surgeon experience allows very large or very complex resections, such as in a previously irradiated field where spontaneous healing is functionally insufficient or is at high risk of postoperative complications. We demonstrated very satisfactory feasibility and postoperative outcomes with a free flap microvascular reconstruction in this category of patients. TORS and free flap reconstruction has a place as a standard of care in a number of complex situations. ABSTRACT: We reviewed the indications, peroperative feasibility, and postoperative clinical outcomes of our first 50 consecutive patients who underwent free flap reconstruction after TORS for complex pharyngeal defects at our institution. We analyzed indications according to previous radiotherapy, the size of the resection, and the transoral exposure of critical structures. We reviewed surgical data, postoperative complications, and functional outcomes comprising tracheostomy and alimentation management. Indications were upfront surgery (34%), a second primary surgery after radiotherapy (28%), or salvage surgery after chemoradiotherapy failure (38%). Localizations were the tongue base (44%), tonsillar fossa (28%), pharyngeal wall (22%), and soft palate (6%). T-classifications were T1 (6%), T2 (52%), T3 (20%), and T4 (22%). The mean length of the surgery was 574 min. Two patients were intraoperatively converted to a conventional approach at the beginning of the learning curve. In conclusion, TORS and free flap reconstruction in complex situations were associated with low rates of postoperative complications and satisfactory functional outcomes. They were, however, associated with a renewed learning curve.
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spelling pubmed-82010822021-06-15 Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction Gorphe, Philippe Temam, Stéphane Moya-Plana, Antoine Leymarie, Nicolas Kolb, Frédéric Bout-Roumazeilles, Apolline Qassemyar, Quentin Benmoussa, Nadia Honart, Jean-François Cancers (Basel) Article SIMPLE SUMMARY: Transoral robotic surgery (TORS) with spontaneous healing is associated with improved quality of life as compared to traditional open surgery in small pharyngeal tumors. Improved surgeon experience allows very large or very complex resections, such as in a previously irradiated field where spontaneous healing is functionally insufficient or is at high risk of postoperative complications. We demonstrated very satisfactory feasibility and postoperative outcomes with a free flap microvascular reconstruction in this category of patients. TORS and free flap reconstruction has a place as a standard of care in a number of complex situations. ABSTRACT: We reviewed the indications, peroperative feasibility, and postoperative clinical outcomes of our first 50 consecutive patients who underwent free flap reconstruction after TORS for complex pharyngeal defects at our institution. We analyzed indications according to previous radiotherapy, the size of the resection, and the transoral exposure of critical structures. We reviewed surgical data, postoperative complications, and functional outcomes comprising tracheostomy and alimentation management. Indications were upfront surgery (34%), a second primary surgery after radiotherapy (28%), or salvage surgery after chemoradiotherapy failure (38%). Localizations were the tongue base (44%), tonsillar fossa (28%), pharyngeal wall (22%), and soft palate (6%). T-classifications were T1 (6%), T2 (52%), T3 (20%), and T4 (22%). The mean length of the surgery was 574 min. Two patients were intraoperatively converted to a conventional approach at the beginning of the learning curve. In conclusion, TORS and free flap reconstruction in complex situations were associated with low rates of postoperative complications and satisfactory functional outcomes. They were, however, associated with a renewed learning curve. MDPI 2021-06-06 /pmc/articles/PMC8201082/ /pubmed/34204149 http://dx.doi.org/10.3390/cancers13112831 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gorphe, Philippe
Temam, Stéphane
Moya-Plana, Antoine
Leymarie, Nicolas
Kolb, Frédéric
Bout-Roumazeilles, Apolline
Qassemyar, Quentin
Benmoussa, Nadia
Honart, Jean-François
Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title_full Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title_fullStr Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title_full_unstemmed Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title_short Indications and Clinical Outcomes of Transoral Robotic Surgery and Free Flap Reconstruction
title_sort indications and clinical outcomes of transoral robotic surgery and free flap reconstruction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201082/
https://www.ncbi.nlm.nih.gov/pubmed/34204149
http://dx.doi.org/10.3390/cancers13112831
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