Cargando…

Enhancement of the Antioxidant and Skin Permeation Properties of Betulin and Its Derivatives

This study investigated the antioxidant activity DPPH, ABTS, and Folin–Ciocalteu methods of betulin (compound 1) and its derivatives (compounds 2–11). Skin permeability and accumulation associated with compounds 1 and 8 were also examined. Identification of the obtained products (compound 2–11) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Günther, Andrzej, Makuch, Edyta, Nowak, Anna, Duchnik, Wiktoria, Kucharski, Łukasz, Pełech, Robert, Klimowicz, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201114/ https://www.ncbi.nlm.nih.gov/pubmed/34198892 http://dx.doi.org/10.3390/molecules26113435

Ejemplares similares

Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives
por: Makuch, Edyta, et al.
Publicado: (2020)

The Effect of Cream and Gel Vehicles on the Percutaneous Absorption and Skin Retention of a New Eugenol Derivative With Antioxidant Activity
por: Makuch, Edyta, et al.
Publicado: (2021)

Enhancement of ibuprofen solubility and skin permeation by conjugation with l-valine alkyl esters
por: Janus, Ewa, et al.
Publicado: (2020)

Epilobium angustifolium L. Essential Oil—Biological Activity and Enhancement of the Skin Penetration of Drugs—In Vitro Study
por: Nowak, Anna, et al.
Publicado: (2021)

Bacterial Cellulose Membrane Containing Epilobium angustifolium L. Extract as a Promising Material for the Topical Delivery of Antioxidants to the Skin
por: Nowak, Anna, et al.
Publicado: (2021)

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan(®) products through human skin
por: Adamiak-Giera, Urszula, et al.
Publicado: (2023)

The effect of alcohols as vehicles on the percutaneous absorption and skin retention of ibuprofen modified with l-valine alkyl esters
por: Ossowicz, Paula, et al.
Publicado: (2020)

Enhancing Transdermal Delivery: Investigating the Impact of Permeation Promoters on Ibuprofen Release and Penetration from Medical Patches—In Vitro Research
por: Bednarczyk, Paulina, et al.
Publicado: (2023)

Novel Naproxen Salts with Increased Skin Permeability
por: Świątek, Ewelina, et al.
Publicado: (2021)

Assessment of the Anti-Inflammatory, Antibacterial and Anti-Aging Properties and Possible Use on the Skin of Hydrogels Containing Epilobium angustifolium L. Extracts
por: Nowak, Anna, et al.
Publicado: (2022)

Corrigendum: Assessment of the anti-inflammatory, antibacterial and anti-aging properties and possible use on the skin of hydrogels containing Epilobium angustifolium L. extracts
por: Nowak, Anna, et al.
Publicado: (2022)

Biologically Active Preparations from the Leaves of Wild Plant Species of the Genus Rubus
por: Kucharski, Łukasz, et al.
Publicado: (2022)

New Ferulic Acid and Amino Acid Derivatives with Increased Cosmeceutical and Pharmaceutical Potential
por: Janus, Ewa, et al.
Publicado: (2022)

In Vitro Human Skin Penetration, Antioxidant and Antimicrobial Activity of Ethanol-Water Extract of Fireweed (Epilobium angustifolium L.)
por: Nowak, Anna, et al.
Publicado: (2021)

Epilobium angustifolium L. Extracts as Valuable Ingredients in Cosmetic and Dermatological Products
por: Nowak, Anna, et al.
Publicado: (2021)

Influence of the Type of Amino Acid on the Permeability and Properties of Ibuprofenates of Isopropyl Amino Acid Esters
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Sustainable UV-Crosslinkable Acrylic Pressure-Sensitive Adhesives for Medical Application
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

New amino acid propyl ester ibuprofenates from synthesis to use in drug delivery systems
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Exploring Alkyl Ester Salts of L-Amino Acid Derivatives of Ibuprofen: Physicochemical Characterization and Transdermal Potential
por: Witkowski, Kordian, et al.
Publicado: (2023)

Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan(®) (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

Permeability of Ibuprofen in the Form of Free Acid and Salts of L-Valine Alkyl Esters from a Hydrogel Formulation through Strat-M™ Membrane and Human Skin
por: Klebeko, Joanna, et al.
Publicado: (2021)

Transdermal Delivery Systems for Ibuprofen and Ibuprofen Modified with Amino Acids Alkyl Esters Based on Bacterial Cellulose
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

Evaluation of the Structural Modification of Ibuprofen on the Penetration Release of Ibuprofen from a Drug-in-Adhesive Matrix Type Transdermal Patch
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Emulsion-Based Gel Loaded with Ibuprofen and Its Derivatives
por: Agboola, Adebukola Abiola, et al.
Publicado: (2023)

Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro
por: Weber, Lisa A., et al.
Publicado: (2020)

High cytotoxicity of betulin towards fish and murine fibroblasts: Is betulin safe for nonneoplastic cells?
por: Małaczewska, Joanna, et al.
Publicado: (2021)

Screening and Characterisation of Antimicrobial Properties of Semisynthetic Betulin Derivatives
por: Haque, Shafiul, et al.
Publicado: (2014)

Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde
por: Bębenek, Ewa, et al.
Publicado: (2019)

Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin
por: Boryczka, Stanisław, et al.
Publicado: (2013)

Anticancer properties of bacterial cellulose membrane containing ethanolic extract of Epilobium angustifolium L
por: Perużyńska, Magdalena, et al.
Publicado: (2023)

Antileishmanial Activity of Semisynthetic Lupane Triterpenoids Betulin and Betulinic Acid Derivatives: Synergistic Effects with Miltefosine
por: Sousa, Maria C., et al.
Publicado: (2014)

Anti-Inflammatory and Anticancer Properties of Birch Bark-Derived Betulin: Recent Developments
por: Tuli, Hardeep Singh, et al.
Publicado: (2021)

Skin Penetration and Permeation Properties of Transcutol®—Neat or Diluted Mixtures
por: Osborne, David W., et al.
Publicado: (2018)

Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy
por: Li, Jiafeng, et al.
Publicado: (2019)

Novel polymeric derivatives of betulin with anticancer activity
por: Niewolik, Daria, et al.
Publicado: (2019)

Methods of Analysis and Identification of Betulin and Its Derivatives
por: Takibayeva, Altynaray T., et al.
Publicado: (2023)

Preactivated thiomers: Permeation enhancing properties
por: Wang, Xueqing, et al.
Publicado: (2012)

Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
por: Drąg-Zalesińska, Małgorzata, et al.
Publicado: (2017)

Preparation and optimization of lidocaine transferosomal gel containing permeation enhancers: a promising approach for enhancement of skin permeation
por: Omar, Mahmoud M, et al.
Publicado: (2019)

Functionalization of Betulinic Acid with Polyphenolic Fragments for the Development of New Amphiphilic Antioxidants
por: Sousa, Joana L. C., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pohj0okemiv0edar23qmjrrrro