Cargando…

VDAC1 Silencing in Cancer Cells Leads to Metabolic Reprogramming That Modulates Tumor Microenvironment

SIMPLE SUMMARY: Tumors are comprised of proliferating cancer cells, and their microenvironment consists of the extracellular matrix, blood vessels, and a variety of tissue cells. The tumor microenvironment functions in cell growth, proliferation, migration, immunity, malignant transformation, and ap...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zerbib, Erez, Arif, Tasleem, Shteinfer-Kuzmine, Anna, Chalifa-Caspi, Vered, Shoshan-Barmatz, Varda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201394/ https://www.ncbi.nlm.nih.gov/pubmed/34200480 http://dx.doi.org/10.3390/cancers13112850

Ejemplares similares

The Mitochondrial Protein VDAC1 at the Crossroads of Cancer Cell Metabolism: The Epigenetic Link
por: Amsalem, Zohar, et al.
Publicado: (2020)

Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States
por: Arif, Tasleem, et al.
Publicado: (2018)

Rewiring of Cancer Cell Metabolism by Mitochondrial VDAC1 Depletion Results in Time-Dependent Tumor Reprogramming: Glioblastoma as a Proof of Concept
por: Arif, Tasleem, et al.
Publicado: (2019)

Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks
por: Pandey, Swaroop Kumar, et al.
Publicado: (2022)

Metabolic Reprograming Via Silencing of Mitochondrial VDAC1 Expression Encourages Differentiation of Cancer Cells
por: Arif, Tasleem, et al.
Publicado: (2019)

VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2020)

Selective induction of cancer cell death by VDAC1‐based peptides and their potential use in cancer therapy
por: Shteinfer‐Kuzmine, Anna, et al.
Publicado: (2018)

Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma
por: Shteinfer-Kuzmine, Anna, et al.
Publicado: (2017)

Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression
por: Pandey, Swaroop Kumar, et al.
Publicado: (2022)

Apoptotic proteins with non-apoptotic activity: expression and function in cancer
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2023)

Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2017)

Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology
por: Verma, Ankit, et al.
Publicado: (2022)

Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo
por: Arif, Tasleem, et al.
Publicado: (2014)

Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo
por: Arif, Tasleem, et al.
Publicado: (2017)

Correction: Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology
por: Verma, Ankit, et al.
Publicado: (2023)

Adverse Effects of Metformin From Diabetes to COVID-19, Cancer, Neurodegenerative Diseases, and Aging: Is VDAC1 a Common Target?
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2021)

The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide
por: Anand, Uttpal, et al.
Publicado: (2022)

Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS
por: Shteinfer-Kuzmine, Anna, et al.
Publicado: (2022)

A VDAC1-Derived N-Terminal Peptide Inhibits Mutant SOD1-VDAC1 Interactions and Toxicity in the SOD1 Model of ALS
por: Shteinfer-Kuzmine, Anna, et al.
Publicado: (2019)

VDAC1: from structure to cancer therapy
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2012)

VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2017)

Overexpression of the mitochondrial anti-viral signaling protein, MAVS, in cancers is associated with cell survival and inflammation
por: Trishna, Sweta, et al.
Publicado: (2023)

VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2019)

SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis
por: Pandey, Swaroop Kumar, et al.
Publicado: (2021)

Pro-Apoptotic and Anti-Cancer Activity of the Vernonanthura Nudiflora Hydroethanolic Extract
por: Nadir, Almog, et al.
Publicado: (2023)

Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide
por: Pittala, Srinivas, et al.
Publicado: (2018)

Editorial: Uncovering the Function of the Mitochondrial Protein VDAC in Health and Disease: From Structure-Function to Novel Therapeutic Strategies
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2017)

VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia
por: Prezma, T, et al.
Publicado: (2013)

VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism
por: Klapper-Goldstein, Hadar, et al.
Publicado: (2020)

Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities
por: Pahima, Hadas, et al.
Publicado: (2018)

Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment
por: Admoni-Elisha, Lee, et al.
Publicado: (2016)

The VDAC1-based R-Tf-D-LP4 Peptide as a Potential Treatment for Diabetes Mellitus
por: Pittala, Srinivas, et al.
Publicado: (2020)

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells
por: Zhang, Enming, et al.
Publicado: (2019)

The Mitochondrial Voltage-Dependent Anion Channel 1, Ca(2+) Transport, Apoptosis, and Their Regulation
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2017)

Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death
por: Rimmerman, N, et al.
Publicado: (2013)

Comparative genomic analysis of clinical and environmental Vibrio vulnificus isolates revealed biotype 3 evolutionary relationships
por: Koton, Yael, et al.
Publicado: (2015)

The dead, hardened floral bracts of dispersal units of wild wheat function as storage for active hydrolases and in enhancing seedling vigor
por: Raviv, Buzi, et al.
Publicado: (2017)

Editorial: Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets
por: Pessoa, João, et al.
Publicado: (2022)

VDAC Modulation of Cancer Metabolism: Advances and Therapeutic Challenges
por: Heslop, Kareem A., et al.
Publicado: (2021)

VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells
por: Zhou, Kai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jgsovf7upqjrbg6lqc2lubi9gq