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Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine-resistant myeloid leukemia cells
Cytarabine is a key chemotherapy drug for treating leukemia; however, chemotherapy-induced multidrug resistance is a major cause of therapy failure or tumor recurrence. Current medical treatment strategies still cannot address the issue of multidrug resistance phenotypes in the treatment of leukemia...
Autores principales: | Tseng, Yu-Hsin, Yang, Rei-Cheng, Chiou, Shyh-Shin, Shieh, Tzong-Ming, Shih, Yin-Hwa, Lin, Pei-Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201441/ https://www.ncbi.nlm.nih.gov/pubmed/34109436 http://dx.doi.org/10.3892/mmr.2021.12204 |
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