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Landscape and selection of vaccine epitopes in SARS-CoV-2
BACKGROUND: Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding und...
Autores principales: | Smith, Christof C., Olsen, Kelly S., Gentry, Kaylee M., Sambade, Maria, Beck, Wolfgang, Garness, Jason, Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Woods, Allison, Fini, Misha, Carpenter, Brandon, Routh, Eric, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Sandor, Adam M., Ting, Jenny P. Y., Weiss, Jared, Krajewski, Krzysztof, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201469/ https://www.ncbi.nlm.nih.gov/pubmed/34127050 http://dx.doi.org/10.1186/s13073-021-00910-1 |
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