Landscape and selection of vaccine epitopes in SARS-CoV-2

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BACKGROUND: Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4(+) T cell, and CD8(+) T cell stimulation. The rationale for this design was to drive both humoral and cellular immunity with high specificity while avoiding und...

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Detalles Bibliográficos
Autores principales: Smith, Christof C., Olsen, Kelly S., Gentry, Kaylee M., Sambade, Maria, Beck, Wolfgang, Garness, Jason, Entwistle, Sarah, Willis, Caryn, Vensko, Steven, Woods, Allison, Fini, Misha, Carpenter, Brandon, Routh, Eric, Kodysh, Julia, O’Donnell, Timothy, Haber, Carsten, Heiss, Kirsten, Stadler, Volker, Garrison, Erik, Sandor, Adam M., Ting, Jenny P. Y., Weiss, Jared, Krajewski, Krzysztof, Grant, Oliver C., Woods, Robert J., Heise, Mark, Vincent, Benjamin G., Rubinsteyn, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201469/
https://www.ncbi.nlm.nih.gov/pubmed/34127050
http://dx.doi.org/10.1186/s13073-021-00910-1
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