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Elevated Hydrostatic Pressure Causes Retinal Degeneration Through Upregulating Lipocalin-2

Elevation of intraocular pressure is a major risk factor for glaucoma development, which causes the loss of retinal ganglion cells (RGCs). Lipocalin 2 (Lcn2) is upregulated in glaucomatous retinae; however, whether Lcn2 is directly involved in glaucoma is debated. In this study, retinal explant cult...

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Detalles Bibliográficos
Autores principales: Yoneshige, Azusa, Hagiyama, Man, Takashima, Yasutoshi, Ueno, Satoru, Inoue, Takao, Kimura, Ryuichiro, Koriyama, Yoshiki, Ito, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201777/
https://www.ncbi.nlm.nih.gov/pubmed/34136483
http://dx.doi.org/10.3389/fcell.2021.664327

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