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Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

Sequence signatures of multidonor broadly neutralizing influenza antibodies can be used to quantify the prevalence of B cells with virus-neutralizing potential to accelerate development of broadly protective vaccine strategies. Antibodies of the same class share similar recognition modes and develop...

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Detalles Bibliográficos
Autores principales:	Chuang, Gwo-Yu, Shen, Chen-Hsiang, Cheung, Crystal Sao-Fong, Gorman, Jason, Creanga, Adrian, Joyce, M. Gordon, Leung, Kwanyee, Rawi, Reda, Wang, Lingshu, Yang, Eun Sung, Yang, Yongping, Zhang, Baoshan, Zhang, Yi, Kanekiyo, Masaru, Zhou, Tongqing, DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Kwong, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201785/ https://www.ncbi.nlm.nih.gov/pubmed/34135892 http://dx.doi.org/10.3389/fimmu.2021.662909

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