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SETD2-mediated H3K14 trimethylation promotes ATR activation and stalled replication fork restart in response to DNA replication stress

Ataxia telangiectasia and Rad3 related (ATR) activation after replication stress involves a cascade of reactions, including replication protein A (RPA) complex loading onto single-stranded DNA and ATR activator loading onto chromatin. The contribution of histone modifications to ATR activation, howe...

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Detalles Bibliográficos
Autores principales:	Zhu, Qian, Yang, Qiaoyan, Lu, Xiaopeng, Wang, Hui, Tong, Lili, Li, Zheng, Liu, Ge, Bao, Yantao, Xu, Xingzhi, Gu, Luo, Yuan, Jian, Liu, Xiangyu, Zhu, Wei-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201831/ https://www.ncbi.nlm.nih.gov/pubmed/34074749 http://dx.doi.org/10.1073/pnas.2011278118

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