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Integrin α(2)β(1)-targeting ferritin nanocarrier traverses the blood–brain barrier for effective glioma chemotherapy

BACKGROUND: Ferritin, the natural iron storage protein complex, self-assembles into a uniform cage-like structure. Human H-ferritin (HFn) has been shown to transverse the blood–brain barrier (BBB) by binding to transferrin receptor 1 (TfR1), which is abundant in endothelial cells and overexpressed i...

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Detalles Bibliográficos
Autores principales:	Huang, Chiun-Wei, Chuang, Chia-Pao, Chen, Yan-Jun, Wang, Hsu-Yuan, Lin, Jia-Jia, Huang, Chiung-Yin, Wei, Kuo-Chen, Huang, Feng-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201891/ https://www.ncbi.nlm.nih.gov/pubmed/34120610 http://dx.doi.org/10.1186/s12951-021-00925-1

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