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cGAS restricts colon cancer development by protecting intestinal barrier integrity

The DNA-sensing enzyme cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) regulates inflammation and immune defense against pathogens and malignant cells. Although cGAS has been shown to exert antitumor effects in several mouse models harboring transplanted tumor cell lines, its...

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Detalles Bibliográficos
Autores principales:	Hu, Shuiqing, Fang, Yan, Chen, Xiang, Cheng, Tianlei, Zhao, Miaoqing, Du, Mingjian, Li, Tuo, Li, Minghao, Zeng, Zhiqun, Wei, Yonglong, Gu, Zhimin, Zhang, Conggang, Sun, Lijun, Chen, Zhijian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201956/ https://www.ncbi.nlm.nih.gov/pubmed/34074794 http://dx.doi.org/10.1073/pnas.2105747118

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