Cargando…

Potent Molecular Feature-based Neutralizing Monoclonal Antibodies as Promising Therapeutics Against SARS-CoV-2 Infection

The 2019–2020 winter was marked by the emergence of a new coronavirus (SARS-CoV-2) related disease (COVID-19), which started in Wuhan, China. Its high human-to-human transmission ability led to a worldwide spread within few weeks and has caused substantial human loss. Mechanical antiviral control ap...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kombe Kombe, Arnaud John, Zahid, Ayesha, Mohammed, Ahmed, Shi, Ronghua, Jin, Tengchuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201996/ https://www.ncbi.nlm.nih.gov/pubmed/34136533 http://dx.doi.org/10.3389/fmolb.2021.670815

Ejemplares similares

Editorial: Host-microbe interaction in SARS-CoV-2 infection: mechanism and intervention
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2023)

Pharmacological Inhibitors of the NLRP3 Inflammasome
por: Zahid, Ayesha, et al.
Publicado: (2019)

Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2021)

CD8(+) T-cell immune escape by SARS-CoV-2 variants of concern
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2022)

Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity
por: Mengist, Hylemariam Mihiretie, et al.
Publicado: (2021)

Identification of Novel Therapeutic Candidates Against SARS-CoV-2 Infections: An Application of RNA Sequencing Toward mRNA Based Nanotherapeutics
por: Khalid, Zunera, et al.
Publicado: (2022)

Corrigendum: Identification of novel therapeutic candidates against SARS-CoV-2 infections: An application of RNA sequencing toward mRNA based nanotherapeutics
por: Khalid, Zunera, et al.
Publicado: (2022)

A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies
por: Metcalfe, Clive
Publicado: (2022)

Targeting heparan sulfate-protein interactions with oligosaccharides and monoclonal antibodies
por: Li, Miaomiao, et al.
Publicado: (2023)

The Role of Anti-EGFR Monoclonal Antibody in mCRC Maintenance Therapy
por: Yuan, Meiqin, et al.
Publicado: (2022)

Production and characterization of monoclonal antibodies for the detection of the hepatitis C core antigen
por: Vidal-Alcántara, Erick Joan, et al.
Publicado: (2023)

Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies
por: Rinaldi, Francesca, et al.
Publicado: (2021)

Immuno-dominant dengue NS1 peptides as antigens for production of monoclonal antibodies
por: Munasinghe, Erandi, et al.
Publicado: (2022)

Detection of Circulating VZV-Glycoprotein E-Specific Antibodies by Chemiluminescent Immunoassay (CLIA) for Varicella–Zoster Diagnosis
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2022)

The Multi-Functional Roles of CCR7 in Human Immunology and as a Promising Therapeutic Target for Cancer Therapeutics
por: Alrumaihi, Faris
Publicado: (2022)

Mastoparans: A Group of Multifunctional α-Helical Peptides With Promising Therapeutic Properties
por: de Santana, Carlos José Correia, et al.
Publicado: (2022)

lncRNAs-EZH2 interaction as promising therapeutic target in cutaneous melanoma
por: Wozniak, Michal, et al.
Publicado: (2023)

Assessment of neutralization susceptibility of Omicron subvariants XBB.1.5 and BQ.1.1 against broad-spectrum neutralizing antibodies through epitopes mapping
por: Shah, Masaud, et al.
Publicado: (2023)

Learned features of antibody-antigen binding affinity
por: Miller, Nathaniel L., et al.
Publicado: (2023)

Characterization and Value Assignment of a Monoclonal Antibody Reference Material, NMIJ RM 6208a, AIST-MAB
por: Kinumi, Tomoya, et al.
Publicado: (2022)

Prepare for the Future: Dissecting the Spike to Seek Broadly Neutralizing Antibodies and Universal Vaccine for Pandemic Coronaviruses
por: Vangelista, Luca, et al.
Publicado: (2020)

Biodegradable manganese-doped hydroxyapatite antitumor adjuvant as a promising photo-therapeutic for cancer treatment
por: Park, Sumin, et al.
Publicado: (2022)

Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications
por: Vanni, Irene, et al.
Publicado: (2020)

Antibodies and Vaccines Target RBD of SARS-CoV-2
por: Min, Long, et al.
Publicado: (2021)

Indian Ethnomedicinal Phytochemicals as Promising Inhibitors of RNA-Binding Domain of SARS-CoV-2 Nucleocapsid Phosphoprotein: An In Silico Study
por: Muthumanickam, Sankar, et al.
Publicado: (2021)

Structural Requirements and Plasticity of Receptor-Binding Domain in Human Coronavirus Spike
por: Li, Yajuan, et al.
Publicado: (2022)

Metabolomics: a promising tool for deciphering metabolic impairment in heavy metal toxicities
por: Akash, Muhammad Sajid Hamid, et al.
Publicado: (2023)

Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations
por: Fredericks, Alger M., et al.
Publicado: (2022)

Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
por: Piepenbrink, Michael S., et al.
Publicado: (2021)

Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production
por: Zhao, Xiaohui, et al.
Publicado: (2021)

PCOLCE Is Potent Prognostic Biomarker and Associates With Immune Infiltration in Gastric Cancer
por: Xiang, Aizhai, et al.
Publicado: (2020)

Exploring potent aldose reductase inhibitors for anti-diabetic (anti-hyperglycemic) therapy: integrating structure-based drug design, and MMGBSA approaches
por: Shahab, Muhammad, et al.
Publicado: (2023)

Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics
por: Fernández-Quintero, Monica L., et al.
Publicado: (2021)

Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases
por: Qi, Huitang, et al.
Publicado: (2021)

Shape Complementarity Optimization of Antibody–Antigen Interfaces: The Application to SARS-CoV-2 Spike Protein
por: De Lauro, Alfredo, et al.
Publicado: (2022)

Clinical and Gene Features of SARS-CoV-2-Positive Recurrence in Patients Recovered From COVID-19
por: Peng, Yuying, et al.
Publicado: (2022)

Editorial: Multiplex Immunohistochemistry/Immunofluorescence Technique: The Potential and Promise for Clinical Application
por: Fincham, Rachel Elizabeth Ann, et al.
Publicado: (2022)

Antigen–Antibody Complex-Guided Exploration of the Hotspots Conferring the Immune-Escaping Ability of the SARS-CoV-2 RBD
por: Fung, Kit-Man, et al.
Publicado: (2022)

Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications
por: Matin, Mohammed M., et al.
Publicado: (2022)

Cytoskeleton-Associated Protein 4, a Promising Biomarker for Tumor Diagnosis and Therapy
por: Li, Shuang-Xi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_edt0cai0lpalcsuv3lsir3o46e