Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy

Neuropathological observations in neurodegenerative synucleinopathies, including Parkinson disease, implicate a pathological role of α-synuclein accumulation in extranigral sites during the prodromal phase of the disease. In a transgenic mouse model of peripheral-to-central neuroinvasion and propaga...

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Detalles Bibliográficos
Autores principales: Ferreira, Nelson, Richner, Mette, van der Laan, Amelia, Bergholdt Jul Christiansen, Ida, Vægter, Christian B, Nyengaard, Jens R, Halliday, Glenda M, Weis, Joachim, Giasson, Benoit I, Mackenzie, Ian R, Jensen, Poul H, Jan, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202146/
https://www.ncbi.nlm.nih.gov/pubmed/34136810
http://dx.doi.org/10.1093/braincomms/fcab104

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