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Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19
Aim: There is a critical need for safe and effective treatments for COVID-19. One possible type of treatment is cellular medicine such as stem cell therapy, but its potential is unclear. Here, our aim was to assess the potential impact of the many cellular medicine trials for COVID-19. Materials &am...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202509/ https://www.ncbi.nlm.nih.gov/pubmed/34114493 http://dx.doi.org/10.2217/rme-2021-0025 |
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author | Kim, Mina Knoepfler, Paul S |
author_facet | Kim, Mina Knoepfler, Paul S |
author_sort | Kim, Mina |
collection | PubMed |
description | Aim: There is a critical need for safe and effective treatments for COVID-19. One possible type of treatment is cellular medicine such as stem cell therapy, but its potential is unclear. Here, our aim was to assess the potential impact of the many cellular medicine trials for COVID-19. Materials & methods: We collected and analyzed data for defined criteria from trial registries. Results: Our data suggest that relatively few of these COVID-19 trials will produce high-level evidence, but that on average they may be somewhat more rigorous than typical cell therapy trials unrelated to COVID-19. Conclusion: Most COVID-19 cellular medicine trials have relatively low potential for rapid, concrete impact. We discuss the findings in the context of the cellular medicine field overall. |
format | Online Article Text |
id | pubmed-8202509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-82025092021-06-15 Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 Kim, Mina Knoepfler, Paul S Regen Med Short Communication Aim: There is a critical need for safe and effective treatments for COVID-19. One possible type of treatment is cellular medicine such as stem cell therapy, but its potential is unclear. Here, our aim was to assess the potential impact of the many cellular medicine trials for COVID-19. Materials & methods: We collected and analyzed data for defined criteria from trial registries. Results: Our data suggest that relatively few of these COVID-19 trials will produce high-level evidence, but that on average they may be somewhat more rigorous than typical cell therapy trials unrelated to COVID-19. Conclusion: Most COVID-19 cellular medicine trials have relatively low potential for rapid, concrete impact. We discuss the findings in the context of the cellular medicine field overall. Future Medicine Ltd 2021-06-11 2021-05 /pmc/articles/PMC8202509/ /pubmed/34114493 http://dx.doi.org/10.2217/rme-2021-0025 Text en © 2021 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Short Communication Kim, Mina Knoepfler, Paul S Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title | Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title_full | Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title_fullStr | Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title_full_unstemmed | Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title_short | Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 |
title_sort | anticipated impact of stem cell and other cellular medicine clinical trials for covid-19 |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202509/ https://www.ncbi.nlm.nih.gov/pubmed/34114493 http://dx.doi.org/10.2217/rme-2021-0025 |
work_keys_str_mv | AT kimmina anticipatedimpactofstemcellandothercellularmedicineclinicaltrialsforcovid19 AT knoepflerpauls anticipatedimpactofstemcellandothercellularmedicineclinicaltrialsforcovid19 |