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Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells
Retinoic acid (RA) is a fundamental regulator of cell cycle and cell differentiation. Using a leukemic patient-derived in vitro model of a non-APL AML, we previously found that RA evokes activation of a macromolecular signaling complex, a signalosome, built of numerous MAPK-pathway-related signaling...
Autores principales: | Kazim, Noor, Yen, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202776/ https://www.ncbi.nlm.nih.gov/pubmed/34136084 http://dx.doi.org/10.18632/oncotarget.27969 |
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