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Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study
BACKGROUND AND AIMS: Regional anaesthesia has been used to reduce acute post-operative pain as well as opioid-related side effects in breast cancer surgery. Erector spinae plane (ESP) block is a relatively new fascial plane block being tried in various surgical procedures. Our study is a double-blin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202792/ https://www.ncbi.nlm.nih.gov/pubmed/34211195 http://dx.doi.org/10.4103/ija.IJA_1426_20 |
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author | Thiagarajan, Prathiba Thota, Raghu S. Divatia, J.V. |
author_facet | Thiagarajan, Prathiba Thota, Raghu S. Divatia, J.V. |
author_sort | Thiagarajan, Prathiba |
collection | PubMed |
description | BACKGROUND AND AIMS: Regional anaesthesia has been used to reduce acute post-operative pain as well as opioid-related side effects in breast cancer surgery. Erector spinae plane (ESP) block is a relatively new fascial plane block being tried in various surgical procedures. Our study is a double-blind randomised trial, designed to prove the efficacy of this block in breast surgeries. METHODS: Seventy female patients scheduled for unilateral breast surgery were enroled in this prospective, randomised, double-blind study. Patients were randomised to group A and group B. All patients received general anaesthesia while group B received additional ultrasound-guided erector spinae block given at thoracic level—T5 with 20ml of 0.25% bupivacaine. Time to first rescue analgesia was the primary outcome. Secondary outcomes were total intraoperative opioid consumption, pain scores over 24 h, post-operative nausea and vomiting and patient satisfaction score at discharge. The Shapiro–Wilk test was used to check the normality of each variable. A comparison was done using Mann–Whitney test and the level of significance was set at 0.05. RESULTS: The median time to first rescue analgesia in group A versus group B was 1 h (1–12h) versus 8 h (1–26h), respectively, with a P value of 0.044. Group B patients had lower pain scores post-operatively and better satisfaction scores at discharge. There was no statistically significant difference in intraoperative fentanyl consumption. CONCLUSION: Ultrasound-guided ESP block with general anaesthesia offers superior post-operative analgesia compared to general anaesthesia alone in patients undergoing unilateral nonreconstructive breast cancer surgeries. |
format | Online Article Text |
id | pubmed-8202792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-82027922021-06-30 Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study Thiagarajan, Prathiba Thota, Raghu S. Divatia, J.V. Indian J Anaesth Original Article BACKGROUND AND AIMS: Regional anaesthesia has been used to reduce acute post-operative pain as well as opioid-related side effects in breast cancer surgery. Erector spinae plane (ESP) block is a relatively new fascial plane block being tried in various surgical procedures. Our study is a double-blind randomised trial, designed to prove the efficacy of this block in breast surgeries. METHODS: Seventy female patients scheduled for unilateral breast surgery were enroled in this prospective, randomised, double-blind study. Patients were randomised to group A and group B. All patients received general anaesthesia while group B received additional ultrasound-guided erector spinae block given at thoracic level—T5 with 20ml of 0.25% bupivacaine. Time to first rescue analgesia was the primary outcome. Secondary outcomes were total intraoperative opioid consumption, pain scores over 24 h, post-operative nausea and vomiting and patient satisfaction score at discharge. The Shapiro–Wilk test was used to check the normality of each variable. A comparison was done using Mann–Whitney test and the level of significance was set at 0.05. RESULTS: The median time to first rescue analgesia in group A versus group B was 1 h (1–12h) versus 8 h (1–26h), respectively, with a P value of 0.044. Group B patients had lower pain scores post-operatively and better satisfaction scores at discharge. There was no statistically significant difference in intraoperative fentanyl consumption. CONCLUSION: Ultrasound-guided ESP block with general anaesthesia offers superior post-operative analgesia compared to general anaesthesia alone in patients undergoing unilateral nonreconstructive breast cancer surgeries. Wolters Kluwer - Medknow 2021-05 2021-05-20 /pmc/articles/PMC8202792/ /pubmed/34211195 http://dx.doi.org/10.4103/ija.IJA_1426_20 Text en Copyright: © 2021 Indian Journal of Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Thiagarajan, Prathiba Thota, Raghu S. Divatia, J.V. Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title | Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title_full | Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title_fullStr | Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title_full_unstemmed | Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title_short | Efficacy of ultrasound-guided erector spinae plane block following breast surgery – A double–blinded randomised, controlled study |
title_sort | efficacy of ultrasound-guided erector spinae plane block following breast surgery – a double–blinded randomised, controlled study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202792/ https://www.ncbi.nlm.nih.gov/pubmed/34211195 http://dx.doi.org/10.4103/ija.IJA_1426_20 |
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