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The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function

Caffeine is one of the world’s most consumed drugs. According to the Washington Post (2015), two billion cups of coffee are consumed per day worldwide. Caffeine is classified as a central nervous system (CNS) stimulant and an organic molecule called methylxanthine. Caffeine has three notable mechani...

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Autores principales: Fiani, Brian, Zhu, Lawrence, Musch, Brian L, Briceno, Sean, Andel, Ross, Sadeq, Nasreen, Ansari, Ali Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202818/
https://www.ncbi.nlm.nih.gov/pubmed/34150383
http://dx.doi.org/10.7759/cureus.15032
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author Fiani, Brian
Zhu, Lawrence
Musch, Brian L
Briceno, Sean
Andel, Ross
Sadeq, Nasreen
Ansari, Ali Z
author_facet Fiani, Brian
Zhu, Lawrence
Musch, Brian L
Briceno, Sean
Andel, Ross
Sadeq, Nasreen
Ansari, Ali Z
author_sort Fiani, Brian
collection PubMed
description Caffeine is one of the world’s most consumed drugs. According to the Washington Post (2015), two billion cups of coffee are consumed per day worldwide. Caffeine is classified as a central nervous system (CNS) stimulant and an organic molecule called methylxanthine. Caffeine has three notable mechanisms of action on the CNS that produce a psychostimulant effect. These effects are responsible for the effect that caffeine has on cognitive function. The effects of caffeine consumption on cognitive function have been demonstrated across several studies involving humans and animals. With the immense number of people consuming caffeine around the world, it is of vital importance to study the effects that this drug has on people’s cognitive function. This literature review provides useful insights on this question through the analysis of caffeine’s effects on cognitive function, along with information on caffeine’s three modes of action. The findings of recent studies show mixed results regarding the effects of caffeine on mood, attention, processing speed, and memory. Current research suggests that if caffeine does have an effect on mood, the most significant changes may be anxiety. Studies did not support caffeine as having any significant effect on attention, but that it did play a role in enhancing processing speed. The majority of the studies reviewed suggest caffeine as having a significant positive effect on both short and long-term memory in adults and the elderly. Current findings warrant continued research on the association of caffeine and the resultant effects on cognitive function.
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spelling pubmed-82028182021-06-17 The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function Fiani, Brian Zhu, Lawrence Musch, Brian L Briceno, Sean Andel, Ross Sadeq, Nasreen Ansari, Ali Z Cureus Endocrinology/Diabetes/Metabolism Caffeine is one of the world’s most consumed drugs. According to the Washington Post (2015), two billion cups of coffee are consumed per day worldwide. Caffeine is classified as a central nervous system (CNS) stimulant and an organic molecule called methylxanthine. Caffeine has three notable mechanisms of action on the CNS that produce a psychostimulant effect. These effects are responsible for the effect that caffeine has on cognitive function. The effects of caffeine consumption on cognitive function have been demonstrated across several studies involving humans and animals. With the immense number of people consuming caffeine around the world, it is of vital importance to study the effects that this drug has on people’s cognitive function. This literature review provides useful insights on this question through the analysis of caffeine’s effects on cognitive function, along with information on caffeine’s three modes of action. The findings of recent studies show mixed results regarding the effects of caffeine on mood, attention, processing speed, and memory. Current research suggests that if caffeine does have an effect on mood, the most significant changes may be anxiety. Studies did not support caffeine as having any significant effect on attention, but that it did play a role in enhancing processing speed. The majority of the studies reviewed suggest caffeine as having a significant positive effect on both short and long-term memory in adults and the elderly. Current findings warrant continued research on the association of caffeine and the resultant effects on cognitive function. Cureus 2021-05-14 /pmc/articles/PMC8202818/ /pubmed/34150383 http://dx.doi.org/10.7759/cureus.15032 Text en Copyright © 2021, Fiani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Fiani, Brian
Zhu, Lawrence
Musch, Brian L
Briceno, Sean
Andel, Ross
Sadeq, Nasreen
Ansari, Ali Z
The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title_full The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title_fullStr The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title_full_unstemmed The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title_short The Neurophysiology of Caffeine as a Central Nervous System Stimulant and the Resultant Effects on Cognitive Function
title_sort neurophysiology of caffeine as a central nervous system stimulant and the resultant effects on cognitive function
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202818/
https://www.ncbi.nlm.nih.gov/pubmed/34150383
http://dx.doi.org/10.7759/cureus.15032
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