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Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin

Oxaliplatin resistance can develop in colorectal cancer (CRC), which may involve inhibition of ferroptosis, although further research is needed to understand this potential mechanism. We evaluated CRC cells with acquired oxaliplatin resistance (HCT116-Or) or congenital resistance (H716) to determine...

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Detalles Bibliográficos
Autores principales:	Yang, Changshun, Zhang, Yu, Lin, Shengtao, Liu, Yi, Li, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202845/ https://www.ncbi.nlm.nih.gov/pubmed/33819186 http://dx.doi.org/10.18632/aging.202774

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