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miR-485 inhibits histone deacetylase HDAC5, HIF1α and PFKFB3 expression to alleviate epilepsy in cellular and rodent models

We investigated the role of microRNA (miR)-485 and its downstream signaling molecules on mediating epilepsy in cellular and rat models. We established a cellular epilepsy model by exposing hippocampal neurons to magnesium and a rat model by treating ICR mice with lithium chloride (127 mg/kg) and pil...

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Detalles Bibliográficos
Autores principales:	Pan, Wei, Song, Xingyu, Hu, Qibo, Zhang, Yunfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202868/ https://www.ncbi.nlm.nih.gov/pubmed/34021541 http://dx.doi.org/10.18632/aging.203058

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