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Autophagy deficiency downregulates O(6)methylguanine-DNA methyltransferase and increases chemosensitivity of liver cancer cells

It is known that autophagy-deficient cells are prone to DNA damage, but the specific role of autophagy in DNA damage repair is not fully known. Here, we show that autophagy-deficient liver cancer cells exhibit increased DNA damage caused by the chemotherapeutic agent epirubicin. Autophagy deficiency...

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Detalles Bibliográficos
Autores principales:	Hou, Xiaojuan, Shao, Changchun, Sun, Kai, Li, Rong, Gao, Lu, Meng, Yan, Jing, Yingying, Wei, Lixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202878/ https://www.ncbi.nlm.nih.gov/pubmed/34031266 http://dx.doi.org/10.18632/aging.203044

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