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Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment
cDNA microarray data conducted by our group revealed overexpression of CXCL2 and CXCL8 in ovarian cancer (OC) microenvironment. Herein, we have proven that the chemokine receptor, CXCR2, is a pivotal molecule in re-sensitizing OC to cisplatin, and its inhibition decreases cell proliferation, viabili...
Autores principales: | Henriques, Taciane Barbosa, dos Santos, Diandra Zipinotti, dos Santos Guimarães, Isabella, Tessarollo, Nayara Gusmão, Lyra-Junior, Paulo Cilas Morais, Mesquita, Patricia, Pádua, Diana, Amaral, Ana Luisa, Cavadas, Bruno, Pereira, Luisa, Silva, Ian Victor, Almeida, Raquel Maria da Silva Graça, Rangel, Leticia Batista Azevedo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202899/ https://www.ncbi.nlm.nih.gov/pubmed/34038868 http://dx.doi.org/10.18632/aging.203074 |
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