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Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1–smad/p38MAPK–lnc865/lnc556–miR-29b-2-5p–STAT3 signal pathway
Pulmonary fibrosis is a common pulmonary interstitial disease of pathogenesis without effective drugs for treatment. Therefore, discovering new and effective drugs is urgently needed. In the present study, we prepared a novel compound named acetyl oxygen benzoate engeletin ester (AOBEE), investigate...
Autores principales: | Shen, Ke, Li, Ruiqiong, Zhang, Xiaoli, Qu, Guiwu, Li, Rongrong, Wang, Youlei, Liu, Bo, Lv, Changjun, Li, Minge, Song, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202900/ https://www.ncbi.nlm.nih.gov/pubmed/33929970 http://dx.doi.org/10.18632/aging.202975 |
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