Cargando…

Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1–smad/p38MAPK–lnc865/lnc556–miR-29b-2-5p–STAT3 signal pathway

Pulmonary fibrosis is a common pulmonary interstitial disease of pathogenesis without effective drugs for treatment. Therefore, discovering new and effective drugs is urgently needed. In the present study, we prepared a novel compound named acetyl oxygen benzoate engeletin ester (AOBEE), investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Ke, Li, Ruiqiong, Zhang, Xiaoli, Qu, Guiwu, Li, Rongrong, Wang, Youlei, Liu, Bo, Lv, Changjun, Li, Minge, Song, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202900/
https://www.ncbi.nlm.nih.gov/pubmed/33929970
http://dx.doi.org/10.18632/aging.202975

Ejemplares similares