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Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely on ivermectin, which suppresses symptoms c...

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Detalles Bibliográficos
Autores principales:	Bah, Germanus S., Schneckener, Sebastian, Hahnel, Steffen R., Bayang, Nicolas H., Fieseler, Helena, Schmuck, Gabriele M., Krebber, Ralph, Sarr, Anouk, Terjung, Carsten, Ngangyung, Henrietta F., Ekale, David D., Mfopit, Youssouf M., Rufener, Lucien, Graham-Brown, John, Tanya, Vincent N., Glenschek-Sieberth, Martin, Kulke, Daniel, Makepeace, Benjamin L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202924/ https://www.ncbi.nlm.nih.gov/pubmed/34077488 http://dx.doi.org/10.1371/journal.ppat.1009601

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