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Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study

BACKGROUND: Periprosthetic fractures (PPFs) are a growing matter for orthopaedic surgeons, and patients with PPFs may represent a frail target in the case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The purpose of this study is to investigate whether hospital reorganis...

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Autores principales: Zagra, Luigi, D’Apolito, Rocco, Guindani, Nicola, Zatti, Giovanni, Rivera, Fabrizio, Ravasi, Flavio, Mosconi, Mario, Momoli, Alberto, Massè, Alessandro, Franceschini, Massimo, D’Angelo, Fabio, Dallari, Dante, Catani, Fabio, Casiraghi, Alessandro, Bove, Federico, Castelli, Claudio Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202961/
https://www.ncbi.nlm.nih.gov/pubmed/34128114
http://dx.doi.org/10.1186/s10195-021-00584-w
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author Zagra, Luigi
D’Apolito, Rocco
Guindani, Nicola
Zatti, Giovanni
Rivera, Fabrizio
Ravasi, Flavio
Mosconi, Mario
Momoli, Alberto
Massè, Alessandro
Franceschini, Massimo
D’Angelo, Fabio
Dallari, Dante
Catani, Fabio
Casiraghi, Alessandro
Bove, Federico
Castelli, Claudio Carlo
author_facet Zagra, Luigi
D’Apolito, Rocco
Guindani, Nicola
Zatti, Giovanni
Rivera, Fabrizio
Ravasi, Flavio
Mosconi, Mario
Momoli, Alberto
Massè, Alessandro
Franceschini, Massimo
D’Angelo, Fabio
Dallari, Dante
Catani, Fabio
Casiraghi, Alessandro
Bove, Federico
Castelli, Claudio Carlo
author_sort Zagra, Luigi
collection PubMed
description BACKGROUND: Periprosthetic fractures (PPFs) are a growing matter for orthopaedic surgeons, and patients with PPFs may represent a frail target in the case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The purpose of this study is to investigate whether hospital reorganisations during the most severe phase of the SARS-CoV-2 pandemic affected standards of care and early outcomes of patients treated for PPFs in Northern Italy. MATERIALS AND METHODS: Data were retrieved from a multicentre retrospective orthopaedics and traumatology database, including 14 hospitals. The following parameters were studied: demographics, results of nasopharyngeal swabs, prevalence of coronavirus disease 2019 (COVID-19), comorbidities, general health status (EQ-5D-5L Score), frailty (Clinical Frailty Scale, CFS), pain (visual analogue scale, VAS), anaesthesiologic risk (American Society of Anaesthesiology Score, ASA Score), classification (unified classification system, UCS), type of operation and anaesthesia, in-hospital and early complications (Clavien–Dindo Classification, CDC), and length of stay (LOS). Data were analysed by means of descriptive statistics. Out of 1390 patients treated for any reason, 38 PPFs were included. RESULTS: Median age was 81 years (range 70–96 years). Twenty-three patients (60.5%) were swabbed on admission, and two of them (5.3%) tested positive; in three patients (7.9%), the diagnosis of COVID-19 was established on a clinical and radiological basis. Two more patients tested positive post-operatively, and one of them died due to COVID-19. Thirty-three patients (86.8%) presented a proximal femoral PPF. Median ASA Score was 3 (range, 1–4), median VAS score on admission was 3 (range, 0–6), median CFS was 4 (range, 1–8), median EQ-5D-5L Score was 3 in each one of the categories (range, 1–5). Twenty-three patients (60.5%) developed post-operative complications, and median CDC grade was 3 (range, 1–5). The median LOS was 12.8 days (range 2–36 days), and 21 patients (55.3%) were discharged home. CONCLUSIONS: The incidence of PPFs did not seem to change during the lockdown. Patients were mainly elderly with comorbidities, and complications were frequently recorded post-operatively. Despite the difficult period for the healthcare system, hospitals were able to provide effective conventional surgical treatments for PPFs, which were not negatively influenced by the reorganisation. Continued efforts are required to optimise the treatment of these frail patients in the period of the pandemic, minimising the risk of contamination, and to limit the incidence of PPFs in the future. LEVEL OF EVIDENCE: IV.
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spelling pubmed-82029612021-06-15 Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study Zagra, Luigi D’Apolito, Rocco Guindani, Nicola Zatti, Giovanni Rivera, Fabrizio Ravasi, Flavio Mosconi, Mario Momoli, Alberto Massè, Alessandro Franceschini, Massimo D’Angelo, Fabio Dallari, Dante Catani, Fabio Casiraghi, Alessandro Bove, Federico Castelli, Claudio Carlo J Orthop Traumatol Original Article BACKGROUND: Periprosthetic fractures (PPFs) are a growing matter for orthopaedic surgeons, and patients with PPFs may represent a frail target in the case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The purpose of this study is to investigate whether hospital reorganisations during the most severe phase of the SARS-CoV-2 pandemic affected standards of care and early outcomes of patients treated for PPFs in Northern Italy. MATERIALS AND METHODS: Data were retrieved from a multicentre retrospective orthopaedics and traumatology database, including 14 hospitals. The following parameters were studied: demographics, results of nasopharyngeal swabs, prevalence of coronavirus disease 2019 (COVID-19), comorbidities, general health status (EQ-5D-5L Score), frailty (Clinical Frailty Scale, CFS), pain (visual analogue scale, VAS), anaesthesiologic risk (American Society of Anaesthesiology Score, ASA Score), classification (unified classification system, UCS), type of operation and anaesthesia, in-hospital and early complications (Clavien–Dindo Classification, CDC), and length of stay (LOS). Data were analysed by means of descriptive statistics. Out of 1390 patients treated for any reason, 38 PPFs were included. RESULTS: Median age was 81 years (range 70–96 years). Twenty-three patients (60.5%) were swabbed on admission, and two of them (5.3%) tested positive; in three patients (7.9%), the diagnosis of COVID-19 was established on a clinical and radiological basis. Two more patients tested positive post-operatively, and one of them died due to COVID-19. Thirty-three patients (86.8%) presented a proximal femoral PPF. Median ASA Score was 3 (range, 1–4), median VAS score on admission was 3 (range, 0–6), median CFS was 4 (range, 1–8), median EQ-5D-5L Score was 3 in each one of the categories (range, 1–5). Twenty-three patients (60.5%) developed post-operative complications, and median CDC grade was 3 (range, 1–5). The median LOS was 12.8 days (range 2–36 days), and 21 patients (55.3%) were discharged home. CONCLUSIONS: The incidence of PPFs did not seem to change during the lockdown. Patients were mainly elderly with comorbidities, and complications were frequently recorded post-operatively. Despite the difficult period for the healthcare system, hospitals were able to provide effective conventional surgical treatments for PPFs, which were not negatively influenced by the reorganisation. Continued efforts are required to optimise the treatment of these frail patients in the period of the pandemic, minimising the risk of contamination, and to limit the incidence of PPFs in the future. LEVEL OF EVIDENCE: IV. Springer International Publishing 2021-06-14 2021-12 /pmc/articles/PMC8202961/ /pubmed/34128114 http://dx.doi.org/10.1186/s10195-021-00584-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Zagra, Luigi
D’Apolito, Rocco
Guindani, Nicola
Zatti, Giovanni
Rivera, Fabrizio
Ravasi, Flavio
Mosconi, Mario
Momoli, Alberto
Massè, Alessandro
Franceschini, Massimo
D’Angelo, Fabio
Dallari, Dante
Catani, Fabio
Casiraghi, Alessandro
Bove, Federico
Castelli, Claudio Carlo
Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title_full Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title_fullStr Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title_full_unstemmed Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title_short Do standards of care and early outcomes of periprosthetic fractures change during the COVID-19 pandemic? A multicentre study
title_sort do standards of care and early outcomes of periprosthetic fractures change during the covid-19 pandemic? a multicentre study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202961/
https://www.ncbi.nlm.nih.gov/pubmed/34128114
http://dx.doi.org/10.1186/s10195-021-00584-w
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