Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association

The co-occurrence of autoimmune hepatitis (AIH) and pernicious anemia (PA) is extremely rare. We present a case of a 70-year-old woman with AIH who presented for the evaluation of poor appetite and weight loss. Laboratory studies were significant for microcytic anemia, B12, and iron deficiency. Esop...

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Autores principales: Riaz, Amir, Khan, Sikandar, Miret, Rafael, Bejarano, Pablo, Ur Rahman, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203103/
https://www.ncbi.nlm.nih.gov/pubmed/34150396
http://dx.doi.org/10.7759/cureus.15045
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author Riaz, Amir
Khan, Sikandar
Miret, Rafael
Bejarano, Pablo
Ur Rahman, Asad
author_facet Riaz, Amir
Khan, Sikandar
Miret, Rafael
Bejarano, Pablo
Ur Rahman, Asad
author_sort Riaz, Amir
collection PubMed
description The co-occurrence of autoimmune hepatitis (AIH) and pernicious anemia (PA) is extremely rare. We present a case of a 70-year-old woman with AIH who presented for the evaluation of poor appetite and weight loss. Laboratory studies were significant for microcytic anemia, B12, and iron deficiency. Esophagogastroduodenoscopy showed diffuse gastric mucosal atrophy, and the pathology from the body of the stomach showed chronic gastritis. Additional testing was positive for parietal cell antibody and intrinsic factor blocking antibody, confirming the diagnosis of PA. To the best of our knowledge, there is only one documented case of AIH associated with PA.
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spelling pubmed-82031032021-06-17 Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association Riaz, Amir Khan, Sikandar Miret, Rafael Bejarano, Pablo Ur Rahman, Asad Cureus Gastroenterology The co-occurrence of autoimmune hepatitis (AIH) and pernicious anemia (PA) is extremely rare. We present a case of a 70-year-old woman with AIH who presented for the evaluation of poor appetite and weight loss. Laboratory studies were significant for microcytic anemia, B12, and iron deficiency. Esophagogastroduodenoscopy showed diffuse gastric mucosal atrophy, and the pathology from the body of the stomach showed chronic gastritis. Additional testing was positive for parietal cell antibody and intrinsic factor blocking antibody, confirming the diagnosis of PA. To the best of our knowledge, there is only one documented case of AIH associated with PA. Cureus 2021-05-15 /pmc/articles/PMC8203103/ /pubmed/34150396 http://dx.doi.org/10.7759/cureus.15045 Text en Copyright © 2021, Riaz et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Riaz, Amir
Khan, Sikandar
Miret, Rafael
Bejarano, Pablo
Ur Rahman, Asad
Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title_full Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title_fullStr Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title_full_unstemmed Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title_short Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association
title_sort autoimmune hepatitis with concomitant pernicious anemia: a rare association
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203103/
https://www.ncbi.nlm.nih.gov/pubmed/34150396
http://dx.doi.org/10.7759/cureus.15045
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