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Cerebral hemodynamic alterations in patients with Covid-19
BACKGROUND/AIM: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. MATERIA...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203147/ https://www.ncbi.nlm.nih.gov/pubmed/33021761 http://dx.doi.org/10.3906/sag-2006-203 |
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author | SONKAYA, Ali Rıza ÖZTÜRK, Bilgin KARADAŞ, Ömer |
author_facet | SONKAYA, Ali Rıza ÖZTÜRK, Bilgin KARADAŞ, Ömer |
author_sort | SONKAYA, Ali Rıza |
collection | PubMed |
description | BACKGROUND/AIM: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. MATERIALS AND METHODS: The sample of this study included 20 patients hospitalized in our clinic diagnosed with Covid-19 via PCR modality and 20 healthy volunteers of similar age and sex. Bilateral middle cerebral arteries were investigated with transcranial Doppler ultrasonography. Basal cerebral blood flow velocities and vasomotor reactivity rates were determined and statistically compared. RESULTS: When patient and control groups were compared, the mean blood flow velocity was found to be higher in Covid-19 patients than in the healthy volunteers and it was statistically significant (P = 0.00). The mean vasomotor reactivity rates values were found to be lower in the Covid-19 group than the healthy group and was also statistically significant (P = 0.00). CONCLUSION: An increase in basal cerebral blood velocity and a decrease in vasomotor reactivity rates in patients with Covid-19 can be considered as an indicator of dysfunction of cerebral hemodynamics in the central nervous system and this can be evaluated as a result of endothelial dysfunction. |
format | Online Article Text |
id | pubmed-8203147 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-82031472021-06-24 Cerebral hemodynamic alterations in patients with Covid-19 SONKAYA, Ali Rıza ÖZTÜRK, Bilgin KARADAŞ, Ömer Turk J Med Sci Article BACKGROUND/AIM: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. MATERIALS AND METHODS: The sample of this study included 20 patients hospitalized in our clinic diagnosed with Covid-19 via PCR modality and 20 healthy volunteers of similar age and sex. Bilateral middle cerebral arteries were investigated with transcranial Doppler ultrasonography. Basal cerebral blood flow velocities and vasomotor reactivity rates were determined and statistically compared. RESULTS: When patient and control groups were compared, the mean blood flow velocity was found to be higher in Covid-19 patients than in the healthy volunteers and it was statistically significant (P = 0.00). The mean vasomotor reactivity rates values were found to be lower in the Covid-19 group than the healthy group and was also statistically significant (P = 0.00). CONCLUSION: An increase in basal cerebral blood velocity and a decrease in vasomotor reactivity rates in patients with Covid-19 can be considered as an indicator of dysfunction of cerebral hemodynamics in the central nervous system and this can be evaluated as a result of endothelial dysfunction. The Scientific and Technological Research Council of Turkey 2021-04-30 /pmc/articles/PMC8203147/ /pubmed/33021761 http://dx.doi.org/10.3906/sag-2006-203 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article SONKAYA, Ali Rıza ÖZTÜRK, Bilgin KARADAŞ, Ömer Cerebral hemodynamic alterations in patients with Covid-19 |
title | Cerebral hemodynamic alterations in patients with Covid-19 |
title_full | Cerebral hemodynamic alterations in patients with Covid-19 |
title_fullStr | Cerebral hemodynamic alterations in patients with Covid-19 |
title_full_unstemmed | Cerebral hemodynamic alterations in patients with Covid-19 |
title_short | Cerebral hemodynamic alterations in patients with Covid-19 |
title_sort | cerebral hemodynamic alterations in patients with covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203147/ https://www.ncbi.nlm.nih.gov/pubmed/33021761 http://dx.doi.org/10.3906/sag-2006-203 |
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