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Modeling and characterization of inter-individual variability in CD8 T cell responses in mice

To develop vaccines it is mandatory yet challenging to account for inter-individual variability during immune responses. Even in laboratory mice, T cell responses of single individuals exhibit a high heterogeneity that may come from genetic backgrounds, intra-specific processes (e.g. antigen-process...

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Detalles Bibliográficos
Autores principales: Audebert, Chloe, Laubreton, Daphné, Arpin, Christophe, Gandrillon, Olivier, Marvel, Jacqueline, Crauste, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203221/
https://www.ncbi.nlm.nih.gov/pubmed/33554899
http://dx.doi.org/10.3233/ISB-200205