Cargando…

Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine

BACKGROUND: Skeletal muscle ion channelopathies include non-dystrophic myotonias (NDM), periodic paralyses (PP), congenital myasthenic syndrome, and recently identified congenital myopathies. The treatment of these diseases is mainly symptomatic, aimed at reducing muscle excitability in NDM or modif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desaphy, Jean-François, Altamura, Concetta, Vicart, Savine, Fontaine, Bertrand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Systematic Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203248/ https://www.ncbi.nlm.nih.gov/pubmed/33325393 http://dx.doi.org/10.3233/JND-200582

Ejemplares similares

Editorial: New Insights in Skeletal Muscle Channelopathies - A Rapidly Expanding Field
por: Maggi, Lorenzo, et al.
Publicado: (2020)

Ion Channel Gene Mutations Causing Skeletal Muscle Disorders: Pathomechanisms and Opportunities for Therapy
por: Maggi, Lorenzo, et al.
Publicado: (2021)

Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery
por: Imbrici, Paola, et al.
Publicado: (2016)

Ion Channel Involvement in Tumor Drug Resistance
por: Altamura, Concetta, et al.
Publicado: (2022)

Toward precision medicine in myotonic syndromes
por: De Bellis, Michela, et al.
Publicado: (2017)

Measuring quality of life impairment in skeletal muscle channelopathies
por: Sansone, V A, et al.
Publicado: (2012)

Skeletal muscle Ca(V)1.1 channelopathies
por: Flucher, Bernhard E.
Publicado: (2020)

Immersive and Non-Immersive Virtual Reality for Pain and Anxiety Management in Pediatric Patients with Hematological or Solid Cancer: A Systematic Review
por: Comparcini, Dania, et al.
Publicado: (2023)

Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies
por: Imbrici, Paola, et al.
Publicado: (2016)

COVID‐19 infection and vaccination in patients with skeletal muscle channelopathies
por: Vivekanandam, Vinojini, et al.
Publicado: (2022)

Precision Medicine and cardiac channelopathies: when dreams meet reality
por: Gnecchi, Massimiliano, et al.
Publicado: (2021)

Sodium channelopathies of skeletal muscle result from gain or loss of function
por: Jurkat-Rott, Karin, et al.
Publicado: (2010)

Imaging alterations in skeletal muscle channelopathies: a study in 15 patients
por: Maggi, Lorenzo, et al.
Publicado: (2015)

Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment
por: Altamura, Concetta, et al.
Publicado: (2021)

Muscle channelopathies and electrophysiological approach
por: Cherian, Ajith, et al.
Publicado: (2008)

Ion Channels in Multiple Myeloma: Pathogenic Role and Therapeutic Perspectives
por: Saltarella, Ilaria, et al.
Publicado: (2022)

Ion Transporters, Channelopathies, and Glucose Disorders
por: Demirbilek, Huseyin, et al.
Publicado: (2019)

Clinical Diversity of SCN4A-Mutation-Associated Skeletal Muscle Sodium Channelopathy
por: Lee, Sang-Chan, et al.
Publicado: (2009)

Phenotypic heterogeneity in skeletal muscle sodium channelopathies: A case report and literature review
por: Saleem, Rashid, et al.
Publicado: (2013)

Racial Disparities in Ion Channelopathies and Inherited Cardiovascular Diseases Associated With Sudden Cardiac Death
por: Chahine, Mohamed, et al.
Publicado: (2022)

Towards Zebrafish Models of CNS Channelopathies
por: Kolesnikova, Tatiana O., et al.
Publicado: (2022)

Structural Heart Alterations in Brugada Syndrome: Is it Really a Channelopathy? A Systematic Review
por: Oliva, Antonio, et al.
Publicado: (2022)

State of the art in hereditary muscle channelopathies
por: Jurkat-Rott, K., et al.
Publicado: (2010)

Channelopathies
por: Kim, June-Bum
Publicado: (2014)

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome
por: Wilders, Ronald
Publicado: (2012)

Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies
por: Kanner, Scott A., et al.
Publicado: (2020)

Editorial: Emerging talents in pharmacology of ion channels and channelopathies 2022
por: Yakubovich, Daniel
Publicado: (2023)

News and views on ion channels in cancer: is cancer a channelopathy?
por: Bell, Damian C., et al.
Publicado: (2023)

A204E mutation in Na(v)1.4 DIS3 exerts gain- and loss-of-function effects that lead to periodic paralysis combining hyper- with hypo-kalaemic signs
por: Kokunai, Yosuke, et al.
Publicado: (2018)

Substitutions of the S4DIV R2 residue (R1451) in Na(V)1.4 lead to complex forms of paramyotonia congenita and periodic paralyses
por: Poulin, Hugo, et al.
Publicado: (2018)

Genetic testing for long QT syndrome and the category of cardiac ion channelopathies
por: Modell, Stephen M., et al.
Publicado: (2012)

Cancer as a channelopathy: ion channels and pumps in tumor development and progression
por: Litan, Alisa, et al.
Publicado: (2015)

I-13 Muscle ryanodine receptor in congenital myopathies and channelopathies
por: Treves, S., et al.
Publicado: (2011)

Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options
por: Camerino, Giulia Maria, et al.
Publicado: (2019)

Cardiac sodium channelopathies
por: Amin, Ahmad S., et al.
Publicado: (2009)

Channelopathies – An update 2018
por: Natarajan, K.U., et al.
Publicado: (2019)

ClC-1 chloride channels: state-of-the-art research and future challenges
por: Imbrici, Paola, et al.
Publicado: (2015)

A step ahead toward precision medicine for chronic lymphocytic leukemia
por: Patriarca, Andrea, et al.
Publicado: (2020)

Nanomedicine and Immunotherapy: A Step Further towards Precision Medicine for Glioblastoma
por: Šamec, Neja, et al.
Publicado: (2020)

Molecular subtyping of hepatocellular carcinoma: A step toward precision medicine
por: Wu, Yichao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oj6o0ni782q03jbtn7tsv3682r