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Isovitexin Suppresses Stemness of Lung Cancer Stem-Like Cells through Blockage of MnSOD/CaMKII/AMPK Signaling and Glycolysis Inhibition

BACKGROUND: Manganese superoxide dismutase (MnSOD) has been reported to promote stemness of lung cancer stem-like cells (LCSLCs) which had higher glycolytic rates compared with non-CSLCs. Isovitexin exhibited an inhibitory effect on the stemness of hepatocellular carcinoma cells. However, whether is...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Yuan, Qing, Cao, Xiaocheng, Zhang, Jinlin, Cao, Jianguo, Zhang, Jiansong, Xia, Liqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203360/
https://www.ncbi.nlm.nih.gov/pubmed/34195288
http://dx.doi.org/10.1155/2021/9972057