Cargando…

Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence

OBJECTIVES: Computed tomography (CT) imaging of the clavicula displays the reference standard for forensic bone age diagnostics in adolescents and young adults. Consequently, highest efforts on radiation reduction are warranted. Therefore, the aim of this study was to investigate the feasibility of...

Descripción completa

Detalles Bibliográficos
Autores principales: Gassenmaier, Sebastian, Schaefer, Juergen F., Nikolaou, Konstantin, Esser, Michael, Tsiflikas, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203536/
https://www.ncbi.nlm.nih.gov/pubmed/32725332
http://dx.doi.org/10.1007/s00330-020-07079-y
_version_ 1783708187280539648
author Gassenmaier, Sebastian
Schaefer, Juergen F.
Nikolaou, Konstantin
Esser, Michael
Tsiflikas, Ilias
author_facet Gassenmaier, Sebastian
Schaefer, Juergen F.
Nikolaou, Konstantin
Esser, Michael
Tsiflikas, Ilias
author_sort Gassenmaier, Sebastian
collection PubMed
description OBJECTIVES: Computed tomography (CT) imaging of the clavicula displays the reference standard for forensic bone age diagnostics in adolescents and young adults. Consequently, highest efforts on radiation reduction are warranted. Therefore, the aim of this study was to investigate the feasibility of low-dose (LD) CT imaging of the clavicula for age estimation in living adolescents. METHODS: A total of 207 non-contrast chest CT of 144 patients born between 1988 and 2012, performed in 2018 due to various clinical indications, were included in this retrospective study. The mean patient age was 16.9 ± 6.6 years. Patients were divided into a LD (n = 146) and standard-dose (SD; n = 61) group. Image quality, confidence levels, and ossification stages (using the 5-stage classification including the subgroups 2a–3c) were assessed by two radiologists independently. Radiation dose was determined via dosimetry software. RESULTS: Dose simulation with z-axis reduction to depict the clavicula only resulted in a median exposure of 0.1 mSv (IQR: 0.0) in LD compared with 0.9 mSv (IQR: 0.6) in SD (p < 0.001). The median image quality was rated by both readers significantly worse in LD compared with SD on a Likert scale ranging from 1 to 4 with a median of 3 (IQR: 1) versus 4 (IQR: 0; p < 0.001 for both readers). There was an almost perfect agreement for the ossification stages between both readers with a Cohen’s kappa of 0.83 (p < 0.001). Median confidence levels of both readers were not significantly different between LD and SD in the decisive subgroups 2a–3c. CONCLUSIONS: Low-dose CT imaging of the clavicula for age estimation in living adolescents is possible without loss of readers’ confidence. KEY POINTS: • Radiological bone age diagnostics in young delinquents with unknown exact chronological age is important as the judicial systems differentiate between youths and adults. • Low-dose computed tomography scanning of the medial clavicular joint for forensic age estimation is feasible in living adolescents without loss of readers’ confidence. • Sufficient image quality of the medial clavicular joint for forensic bone age diagnostics in living adolescents is achievable using a median dose of 0.1 mSv.
format Online
Article
Text
id pubmed-8203536
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-82035362021-06-17 Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence Gassenmaier, Sebastian Schaefer, Juergen F. Nikolaou, Konstantin Esser, Michael Tsiflikas, Ilias Eur Radiol Forensic Medicine OBJECTIVES: Computed tomography (CT) imaging of the clavicula displays the reference standard for forensic bone age diagnostics in adolescents and young adults. Consequently, highest efforts on radiation reduction are warranted. Therefore, the aim of this study was to investigate the feasibility of low-dose (LD) CT imaging of the clavicula for age estimation in living adolescents. METHODS: A total of 207 non-contrast chest CT of 144 patients born between 1988 and 2012, performed in 2018 due to various clinical indications, were included in this retrospective study. The mean patient age was 16.9 ± 6.6 years. Patients were divided into a LD (n = 146) and standard-dose (SD; n = 61) group. Image quality, confidence levels, and ossification stages (using the 5-stage classification including the subgroups 2a–3c) were assessed by two radiologists independently. Radiation dose was determined via dosimetry software. RESULTS: Dose simulation with z-axis reduction to depict the clavicula only resulted in a median exposure of 0.1 mSv (IQR: 0.0) in LD compared with 0.9 mSv (IQR: 0.6) in SD (p < 0.001). The median image quality was rated by both readers significantly worse in LD compared with SD on a Likert scale ranging from 1 to 4 with a median of 3 (IQR: 1) versus 4 (IQR: 0; p < 0.001 for both readers). There was an almost perfect agreement for the ossification stages between both readers with a Cohen’s kappa of 0.83 (p < 0.001). Median confidence levels of both readers were not significantly different between LD and SD in the decisive subgroups 2a–3c. CONCLUSIONS: Low-dose CT imaging of the clavicula for age estimation in living adolescents is possible without loss of readers’ confidence. KEY POINTS: • Radiological bone age diagnostics in young delinquents with unknown exact chronological age is important as the judicial systems differentiate between youths and adults. • Low-dose computed tomography scanning of the medial clavicular joint for forensic age estimation is feasible in living adolescents without loss of readers’ confidence. • Sufficient image quality of the medial clavicular joint for forensic bone age diagnostics in living adolescents is achievable using a median dose of 0.1 mSv. Springer Berlin Heidelberg 2020-07-28 2020 /pmc/articles/PMC8203536/ /pubmed/32725332 http://dx.doi.org/10.1007/s00330-020-07079-y Text en © The Author(s) 2020, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Forensic Medicine
Gassenmaier, Sebastian
Schaefer, Juergen F.
Nikolaou, Konstantin
Esser, Michael
Tsiflikas, Ilias
Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title_full Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title_fullStr Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title_full_unstemmed Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title_short Forensic age estimation in living adolescents with CT imaging of the clavicula—impact of low-dose scanning on readers’ confidence
title_sort forensic age estimation in living adolescents with ct imaging of the clavicula—impact of low-dose scanning on readers’ confidence
topic Forensic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203536/
https://www.ncbi.nlm.nih.gov/pubmed/32725332
http://dx.doi.org/10.1007/s00330-020-07079-y
work_keys_str_mv AT gassenmaiersebastian forensicageestimationinlivingadolescentswithctimagingoftheclaviculaimpactoflowdosescanningonreadersconfidence
AT schaeferjuergenf forensicageestimationinlivingadolescentswithctimagingoftheclaviculaimpactoflowdosescanningonreadersconfidence
AT nikolaoukonstantin forensicageestimationinlivingadolescentswithctimagingoftheclaviculaimpactoflowdosescanningonreadersconfidence
AT essermichael forensicageestimationinlivingadolescentswithctimagingoftheclaviculaimpactoflowdosescanningonreadersconfidence
AT tsiflikasilias forensicageestimationinlivingadolescentswithctimagingoftheclaviculaimpactoflowdosescanningonreadersconfidence