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Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis

Coxsackievirus B3 (CVB3), is commonly implicated in myocarditis, which can lead to dilated cardiomyopathy, in addition to causing acute pancreatitis and meningitis. Yet, no vaccines are currently available to prevent this infection. Here, we describe the derivation of a live attenuated vaccine virus...

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Detalles Bibliográficos
Autores principales:	Lasrado, Ninaad, Gangaplara, Arunakumar, Massilamany, Chandirasegaran, Arumugam, Rajkumar, Shelbourn, Allison, Rasquinha, Mahima T., Basavalingappa, Rakesh H., Delhon, Gustavo, Xiang, Shi-Hua, Pattnaik, Asit K., Steffen, David, Reddy, Jay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203608/ https://www.ncbi.nlm.nih.gov/pubmed/34127684 http://dx.doi.org/10.1038/s41598-021-90434-w

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