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Meta-analysis of gene signatures and key pathways indicates suppression of JNK pathway as a regulator of chemo-resistance in AML

The pathways and robust deregulated gene signatures involved in AML chemo-resistance are not fully understood. Multiple subgroups of AMLs which are under treatment of various regimens seem to have similar regulatory gene(s) or pathway(s) related to their chemo-resistance phenotype. In this study usi...

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Detalles Bibliográficos
Autores principales: Modarres, Parastoo, Mohamadi Farsani, Farzaneh, Nekouie, Amir Abas, Vallian, Sadeq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203646/
https://www.ncbi.nlm.nih.gov/pubmed/34127725
http://dx.doi.org/10.1038/s41598-021-91864-2

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