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Neuroprotective effects of bone marrow Sca-1(+) cells against age-related retinal degeneration in OPTN E50K mice

Glaucoma is characterized by retinal ganglion cell (RGC) death, the underlying mechanisms of which are still largely unknown. An E50K mutation in the Optineurin (OPTN) gene is a leading cause of normal-tension glaucoma (NTG), which directly affects RGCs in the absence of high intraocular pressure an...

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Detalles Bibliográficos
Autores principales:	Liu, Xinna, Hou, Mingying, Zhang, Shiqi, Zhao, Yutong, Wang, Qi, Jiang, Menglu, Du, Mengxian, Shao, Zhengbo, Yuan, Huiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203676/ https://www.ncbi.nlm.nih.gov/pubmed/34127652 http://dx.doi.org/10.1038/s41419-021-03851-0

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