Higher cMET dependence of sacral compared to clival chordoma cells: contributing to a better understanding of cMET in chordoma

Chordomas are rare slow growing, malignant bone tumors of the axial skeleton with no approved medical treatment. As the majority of chordomas express cMET and its ligand, HGF, and crosstalks between EGFR and MET-signaling exist, we aimed to explore cMET activity in chordoma cell lines and clinical s...

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Detalles Bibliográficos
Autores principales: Lohberger, Birgit, Scheipl, Susanne, Heitzer, Ellen, Quehenberger, Franz, de Jong, Danielle, Szuhai, Karoly, Liegl-Atzwanger, Bernadette, Rinner, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203686/
https://www.ncbi.nlm.nih.gov/pubmed/34127734
http://dx.doi.org/10.1038/s41598-021-92018-0

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