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Neuroprotective effect of selumetinib on acrolein-induced neurotoxicity

Abnormal accumulation of acrolein, an α, β unsaturated aldehyde has been reported as one pathological cause of the CNS neurodegenerative diseases. In the present study, the neuroprotective effect of selumetinib (a MEK–ERK inhibitor) on acrolein-induced neurotoxicity was investigated in vitro using p...

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Detalles Bibliográficos
Autores principales:	Huang, Hui-Ju, Wang, Hsiang-Tsui, Yeh, Ting-Yu, Lin, Bo-Wei, Shiao, Young-Ji, Lo, Yu-Li, Lin, Anya Maan-Yuh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203693/ https://www.ncbi.nlm.nih.gov/pubmed/34127699 http://dx.doi.org/10.1038/s41598-021-91507-6

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