Cargando…

Y disruption, autosomal hypomethylation and poor male lung cancer survival

Lung cancer is the most frequent cause of cancer death worldwide. It affects more men than women, and men generally have worse survival outcomes. We compared gene co-expression networks in affected and unaffected lung tissue from 126 consecutive patients with Stage IA–IV lung cancer undergoing surge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Willis-Owen, Saffron A. G., Domingo-Sabugo, Clara, Starren, Elizabeth, Liang, Liming, Freidin, Maxim B., Arseneault, Madeleine, Zhang, Youming, Lu, Shir Kiong, Popat, Sanjay, Lim, Eric, Nicholson, Andrew G., Riazalhosseini, Yasser, Lathrop, Mark, Cookson, William O. C., Moffatt, Miriam F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203787/ https://www.ncbi.nlm.nih.gov/pubmed/34127738 http://dx.doi.org/10.1038/s41598-021-91907-8

Ejemplares similares

Metabolomic, transcriptomic and genetic integrative analysis reveals important roles of adenosine diphosphate in haemostasis and platelet activation in non‐small‐cell lung cancer
por: Hoang, Long T., et al.
Publicado: (2019)

Global gene regulation during activation of immunoglobulin class switching in human B cells
por: Zhang, Youming, et al.
Publicado: (2016)

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
por: Laura, Gemma, et al.
Publicado: (2021)

A Sarcomatoid Renal Cell Carcinoma with Clear Cell Papillary-Like Primary Tumor and Lymph Node Metastasis: A Diagnostic Conundrum
por: Demko, Nadine, et al.
Publicado: (2022)

Delayed acquisition of airway commensals in antibiotic naïve children and its relationship with wheezing in rural Ecuador
por: Cardenas, Paul A., et al.
Publicado: (2023)

Integrated genomics point to immune vulnerabilities in pleural mesothelioma
por: Nastase, Anca, et al.
Publicado: (2021)

Author Correction: Integrated genomics point to immune vulnerabilities in pleural mesothelioma
por: Nastase, Anca, et al.
Publicado: (2022)

COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix
por: Willis-Owen, Saffron A. G., et al.
Publicado: (2018)

A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines
por: Liang, Liming, et al.
Publicado: (2013)

Vitamin D binding protein variants associate with asthma susceptibility in the Chinese han population
por: Li, Fei, et al.
Publicado: (2011)

An Epigenome-Wide Association Study of Total Serum Immunoglobulin E Concentration
por: Liang, Liming, et al.
Publicado: (2015)

Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
por: Mehdi, Ali, et al.
Publicado: (2017)

Predicting DNA methylation level across human tissues
por: Ma, Baoshan, et al.
Publicado: (2014)

Rational Development of Liquid Biopsy Analysis in Renal Cell Carcinoma
por: Glennon, Kate I., et al.
Publicado: (2021)

Airway microbial communities, smoking and asthma in a general population sample
por: Turek, Elena M., et al.
Publicado: (2021)

Do we use the appropriate controls for the identification of informative methylation markers for early cancer detection?
por: Riazalhosseini, Yasser, et al.
Publicado: (2008)

Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant
por: Zhang, Youming, et al.
Publicado: (2014)

Consequences of VHL Loss on Global DNA Methylome
por: Robinson, Claire M., et al.
Publicado: (2018)

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype
por: Ciano, Margherita, et al.
Publicado: (2019)

Naïve pluripotency is associated with global DNA hypomethylation
por: Leitch, Harry G., et al.
Publicado: (2013)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
por: Naeem, Aishath S., et al.
Publicado: (2017)

Multiomics analysis reveals CT83 is the most specific gene for triple negative breast cancer and its hypomethylation is oncogenic in breast cancer
por: Chen, Chen, et al.
Publicado: (2021)

Hypomethylation of DNA during differentiation of friend erythroleukemia cells
por: Christman, JK, et al.
Publicado: (1980)

Cell–Cell Contact Mediates Gene Expression and Fate Choice of Human Neural Stem/Progenitor Cells
por: McIntyre, William B., et al.
Publicado: (2022)

Loss of chromosome Y leads to down regulation of KDM5D and KDM6C epigenetic modifiers in clear cell renal cell carcinoma
por: Arseneault, Madeleine, et al.
Publicado: (2017)

IRX1 hypomethylation in osteosarcoma metastasis
por: Lu, Jinchang, et al.
Publicado: (2015)

Consistent DNA Hypomethylations in Prostate Cancer
por: Araúzo-Bravo, Marcos J., et al.
Publicado: (2022)

Comparison of Hypomethylator Monotherapy with Hypomethylator plus Chemotherapy for Intermediate/High-Risk MDS or AML: A Meta-Analysis
por: Ji, Jiang, et al.
Publicado: (2020)

Editorial: Insights in human and medical genomics: 2022
por: Roach, Jared C., et al.
Publicado: (2023)

Impact of frontline treatment approach on outcomes in patients with secondary AML with prior hypomethylating agent exposure
por: Short, Nicholas J., et al.
Publicado: (2022)

LINE-1 hypomethylation in familial and sporadic cancer
por: Pavicic, Walter, et al.
Publicado: (2012)

LINE-1 and Alu hypomethylation in mucoepidermoid carcinoma
por: Sirivanichsuntorn, Porntipa, et al.
Publicado: (2013)

Analyses of Hypomethylated Oil Palm Gene Space
por: Low, Eng-Ti L., et al.
Publicado: (2014)

Clinical Results of Hypomethylating Agents in AML Treatment
por: Cruijsen, Marjan, et al.
Publicado: (2014)

Hypomethylation Causes MIR21 Overexpression in Tumors
por: Lu, Jun, et al.
Publicado: (2020)

The association between Alu hypomethylation and the severity of hypertension
por: Thongsroy, Jirapan, et al.
Publicado: (2022)

The genome-wide mutational consequences of DNA hypomethylation
por: Besselink, Nicolle, et al.
Publicado: (2023)

Mutations in CERS3 Cause Autosomal Recessive Congenital Ichthyosis in Humans
por: Radner, Franz P. W., et al.
Publicado: (2013)

In the Wrong Place at the Wrong Time: Microbial Misplacement and Acute Respiratory Distress Syndrome
por: Cookson, William O. C. M., et al.
Publicado: (2020)

A Pandemic Lesson for Global Lung Diseases: Exacerbations Are Preventable
por: Cookson, William, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n01ik8i43t8ob2qfuvrf6i6h8j